Are nonhuman primates good models for SARS?

RJ Hogan - PLoS Medicine, 2006 - journals.plos.org
… of nonhuman primates as good models for SARS [3]. As demonstrated by several groups,
SARS coronavirus (SARS-CoV… host SARSCoV receptor ACE2—is a prerequisite for the SARS-…

An overview of SARS-CoV-2 and animal infection

MAA Mahdy, W Younis, Z Ewaida - Frontiers in veterinary science, 2020 - frontiersin.org
… This review aims to provide an overview of the relation between SARS-CoV-2 and animals.
… They concluded that the three non-human primates simulated several features of COVID-19 …

Severe acute respiratory syndrome-coronavirus infection in aged nonhuman primates is associated with modulated pulmonary and systemic immune responses

CC Clay, N Donart, N Fomukong, JB Knight… - Immunity & …, 2014 - Springer
… at 5 dpi and although titers increased in the juvenile lungs by day 10, no increase in anti-SARS
CoV IgG titers was observed in aged animals (Figure 7B, no significance by unpaired …

Comparison of Dose–Response Relationships for Two Isolates of SARS-CoV-2 in a Nonhuman Primate Model of Inhalational COVID-19

PA Dabisch, JS Sanjak, JA Boydston… - Journal of Aerosol …, 2022 - liebertpub.com
… presentation in nonhuman primates infected with aerosols containing an isolate of the Gamma
variant of SARS-CoV-2 to the results of our previous study with the earlier WA-1 isolate of …

[PDF][PDF] Tissue distribution of SARS-CoV-2 in non-human primates after combined intratracheal and intranasal inoculation

TZ Song, JB Han, X Yang, MH Li… - Science China. Life …, 2021 - researchgate.net
… between the ratios of SARS-CoV-2+ swabs and percentages of SARSCoV-2+ lung lobes. As
… Therefore, nasal SARS-CoV-2 infection markedly enhanced the number of virus particles in …

Evaluation of mRNA-1273 against SARS-CoV-2 B. 1.351 infection in nonhuman primates

KS Corbett, AP Werner, S O'Connell, M Gagne, L Lai… - bioRxiv, 2021 - biorxiv.org
… The emergence of SARS-CoV-2 variants of concern (VOC) 3 … about the efficacy of current
SARS-CoV-2 vaccines against … -immunized human and nonhuman primates (NHP) showed …

Utilizing nonhuman primate models to combat recent COVID‐19/SARSCoV‐2 and viral infectious disease outbreaks

T Kwon - Journal of Medical Primatology, 2024 - Wiley Online Library
… This suggests that viral clearance might not be directly linked to SARSCoV- 2 disease …
Oral and conjunctival exposure of nonhuman primates to Low doses of Ebola Makona virus. …

Developing and validating SARSCoV‐2 assays for nonhuman primate surveillance

JA Yee, A Carpenter, P Nham, B Halley… - Journal of medical …, 2022 - Wiley Online Library
… In early 2020, the California National Primate Research Center implemented
surveillance to address the threat of SARS-CoV-2 infection in its nonhuman primate colony. …

Intestinal immunological events of acute and resolved SARS-CoV-2 infection in non-human primates

S Hua, K Latha, R Marlin, K Benmeziane, L Bossevot… - Mucosal …, 2024 - Elsevier
… By using a non-human primate (NHP) model of SARS-CoV-2 respiratory infection this study
aimed to analyze the related intestinal immune cell changes and to assess whether these …

Nonhuman primates in translational research

AF Tarantal, SC Noctor… - Annual review of …, 2022 - annualreviews.org
… The need for nonhuman primates continues to remain a high priority, which has been …
respiratory syndrome coronavirus 2 (SARS-CoV-2) global pandemic. Nonhuman primates will …