SARS-CoV-2 mRNA-vaccine candidate; COReNAPCIN®, induces robust humoral and cellular immunity in mice and non-human primates

R Alimohammadi, M Porgoo, M Eftekhary, SH Kiaie… - NPJ vaccines, 2022 - nature.com
SARS-CoV-2 specific cellular immunity was also observed in both mice and non-human
primate … Additionally, vaccination protected rhesus macaques from symptomatic SARS-CoV-2 …

Optimization of non-coding regions improves protective efficacy of an mRNA SARS-CoV-2 vaccine in nonhuman primates

MS Gebre, S Rauch, N Roth, J Yu, A Chandrashekar… - BioRxiv, 2021 - biorxiv.org
… against SARS-CoV-2 challenge in nonhuman primates. … of non-coding regions in a
SARS-CoV-2 mRNA vaccine can … efficacy against SARS-CoV-2 challenge in nonhuman primates. …

Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques

NB Mercado, R Zahn, F Wegmann, C Loos… - Nature, 2020 - nature.com
… to various pathogens in both non-human primates and humans. In this … SARS-CoV-2
spike (S) protein, and evaluated their immunogenicity and protective efficacy against SARS-CoV

[HTML][HTML] Viral dynamic modeling of SARS-CoV-2 in non-human primates

A Gonçalves, P Maisonnasse, F Donati, M Albert… - 2020 - europepmc.org
… Based on a nonhuman primate (NHP) model of SARS-CoV-2 infection, we developed a
mathematical model for SARS-CoV-2 that describes viral dynamics in both nasopharyngeal and …

Modeling the viral dynamics of SARS-CoV-2 infection

S Wang, Y Pan, Q Wang, H Miao, AN Brown… - Mathematical …, 2020 - Elsevier
… show that viral dynamics of SARS-CoV-2 infection have a … non-human primates. Using
the model we also evaluate the effect of several potential therapeutic interventions for SARS-CoV-…

B. 1.351 SARS-CoV-2 variant exhibits higher virulence but less viral shedding than that of the ancestral strain in young nonhuman primates

Y Bai, Q He, J Yang, S Lu, Q Mao, F Gao… - Microbiology …, 2022 - Am Soc Microbiol
… pathogenic characteristics of SARS-CoV-2 variants. In addition, nonhuman primates (NHPs)
are suitable animal models for the study of the pathogenic characteristics of SARS-CoV-2 …

Filamentous fungus-produced human monoclonal antibody provides protection against SARS-CoV-2 in hamster and non-human primate models

FK Kaiser, MG Hernandez, N Krüger, E Englund… - Nature …, 2024 - nature.com
… 87G7) that neutralises the SARS-CoV-2 variants of concern (… HuMab 87G7 broadly neutralise
SARS-CoV-2 VOCs in vitro … against the Delta VOC in non-human primates. In summary, …

SARS-CoV-2 infection of rhesus macaques treated early with human COVID-19 convalescent plasma

JD Deere, TD Carroll, J Dutra, L Fritts… - Microbiology …, 2021 - Am Soc Microbiol
… a nonhuman primate (NHP) model of SARS-CoV-2 infection. Rhesus macaques are susceptible
to the virus … The macaque model has been widely used to test candidate SARS-CoV-2 …

Long-term stability and protection efficacy of the RBD-targeting COVID-19 mRNA vaccine in nonhuman primates

H Zhao, TC Wang, XF Li, NN Zhang, L Li… - … and Targeted Therapy, 2021 - nature.com
nonhuman primates infected with SARS-CoV-2. The different pathological changes in
animal models and human patients upon SARS-CoV-2 infection warrant further investigation. …

SARS-CoV-2 infection protects against rechallenge in rhesus macaques

A Chandrashekar, J Liu, AJ Martinot, K McMahan… - Science, 2020 - science.org
SARS-CoV-2 infection induced protective immunity against reexposure in nonhuman primates
Given the near-complete protection in all animals after SARS-CoV-2 rechallenge, we were …