… Although we developed this model to analyze SARS-CoV-2 in non-humanprimates, our results showed many similarities with patterns previously noted in humans. Multiple studies …
… ) of SARS-CoV-2 spike from individuals with acute or convalescent SARS-CoV-2 or a history of SARS-CoV-1 … SARS-CoV-2-reactive human monoclonal antibodies from plasmablasts or …
… The challenge dose was chosen to induce viral loads similar to or higher than those detected in nasal secretions of humans after SARS-CoV-2 infection (27). The primary efficacy end-…
… SARS-CoV-2 in humans. COH04S1 likely confers protection through different immune mechanisms than the mRNA and Ad26 vaccines and may therefore be particularly valuable as a …
… the efficacy of current SARS-CoV-2 vaccines against … SARS-CoV-2 strains 6,22,23 . Additionally, it was reported that sera from mRNA-1273-immunized human and nonhumanprimates …
Z Liu, JFW Chan, J Zhou, M Wang, Q Wang, G Zhang… - Cell research, 2022 - nature.com
… ) consisting of human IgG Fc fragment-conjugated RBD (RBD-Fc) of the original SARS-CoV-… This CF501/RBD-Fc vaccine could elicit extremely potent nAb responses against SARS-CoV…
YM Loo, PM McTamney, RH Arends, RA Gasser Jr… - Medrxiv, 2021 - medrxiv.org
… isotype control mAb or AZD7442 as prophylaxis 3 days prior to SARSCoV-2 challenge. … macaques receiving AZD7442 or AZD7442-YTE as treatment 1 day after SARSCoV-2 infection. …
CY Lee, AC Lowen - Current opinion in virology, 2021 - Elsevier
… to SARS-CoV-2 infection in humans have and will continue to accelerate this development process. Several animal models including mice, hamsters, ferrets, and non-humanprimates …
C Guo, Y Peng, L Lin, X Pan, M Fang, Y Zhao… - Cell Reports …, 2021 - cell.com
… in both mice and humans. … non-humanprimates (NHPs) and found that it could also induce neutralizing antibodies and, most importantly, accelerate the viral clearance upon SARS-CoV-…