Lack of evidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spillover in free-living neotropical non-human primates, Brazil

L Sacchetto, BA Chaves, ER Costa… - Viruses, 2021 - mdpi.com
… to control SARS-CoV-2 in humans and could represent a catastrophe for conservation of …
non-human primates [8,25]. Thus, the current study investigated evidence for SARS-CoV-2 …

Predicting the presence of infectious virus from PCR data: A meta-analysis of SARS-CoV-2 in non-human primates

CE Snedden, JO Lloyd-Smith - PLoS Pathogens, 2024 - journals.plos.org
… Although we developed this model to analyze SARS-CoV-2 in non-human primates, our
results showed many similarities with patterns previously noted in humans. Multiple studies …

The functions of SARS-CoV-2 neutralizing and infection-enhancing antibodies in vitro and in mice and nonhuman primates

D Li, RJ Edwards, K Manne, DR Martinez, A Schäfer… - BioRxiv, 2021 - biorxiv.org
… ) of SARS-CoV-2 spike from individuals with acute or convalescent SARS-CoV-2 or a history
of SARS-CoV-1 … SARS-CoV-2-reactive human monoclonal antibodies from plasmablasts or …

Immune correlates of protection by mRNA-1273 vaccine against SARS-CoV-2 in nonhuman primates

KS Corbett, MC Nason, B Flach, M Gagne, S O'Connell… - Science, 2021 - science.org
… The challenge dose was chosen to induce viral loads similar to or higher than those detected
in nasal secretions of humans after SARS-CoV-2 infection (27). The primary efficacy end-…

Synthetic multiantigen MVA vaccine COH04S1 protects against SARS-CoV-2 in Syrian hamsters and non-human primates

F Chiuppesi, VH Nguyen, Y Park, H Contreras… - npj Vaccines, 2022 - nature.com
SARS-CoV-2 in humans. COH04S1 likely confers protection through different immune
mechanisms than the mRNA and Ad26 vaccines and may therefore be particularly valuable as a …

mRNA-1273 protects against SARS-CoV-2 beta infection in nonhuman primates

KS Corbett, AP Werner, SO Connell, M Gagne… - Nature …, 2021 - nature.com
… the efficacy of current SARS-CoV-2 vaccines against … SARS-CoV-2 strains 6,22,23 .
Additionally, it was reported that sera from mRNA-1273-immunized human and nonhuman primates

A pan-sarbecovirus vaccine induces highly potent and durable neutralizing antibody responses in non-human primates against SARS-CoV-2 Omicron variant

Z Liu, JFW Chan, J Zhou, M Wang, Q Wang, G Zhang… - Cell research, 2022 - nature.com
… ) consisting of human IgG Fc fragment-conjugated RBD (RBD-Fc) of the original SARS-CoV-…
This CF501/RBD-Fc vaccine could elicit extremely potent nAb responses against SARS-CoV

AZD7442 demonstrates prophylactic and therapeutic efficacy in non-human primates and extended half-life in humans

YM Loo, PM McTamney, RH Arends, RA Gasser Jr… - Medrxiv, 2021 - medrxiv.org
… isotype control mAb or AZD7442 as prophylaxis 3 days prior to SARS CoV-2 challenge. …
macaques receiving AZD7442 or AZD7442-YTE as treatment 1 day after SARS CoV-2 infection. …

Animal models for SARS-CoV-2

CY Lee, AC Lowen - Current opinion in virology, 2021 - Elsevier
… to SARS-CoV-2 infection in humans have and will continue to accelerate this development
process. Several animal models including mice, hamsters, ferrets, and non-human primates

A pathogen-like antigen-based vaccine confers immune protection against SARS-CoV-2 in non-human primates

C Guo, Y Peng, L Lin, X Pan, M Fang, Y Zhao… - Cell Reports …, 2021 - cell.com
… in both mice and humans. … non-human primates (NHPs) and found that it could also induce
neutralizing antibodies and, most importantly, accelerate the viral clearance upon SARS-CoV-…