Pharmacological mechanism of immunomodulatory agents for the treatment of severe cases of COVID-19 infection

Z Bahari, Z Jangravi, H Ghoshooni, MR Afarinesh… - Inflammation …, 2021 - Springer
Objective Coronavirus disease 2019 (COVID-19) is a world-wide pandemic caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). To date, treatment of severe

COVID-19: A review of the proposed pharmacological treatments

S Lam, A Lombardi, A Ouanounou - European journal of pharmacology, 2020 - Elsevier
… and continues to grow, the potential severity of the disease and its … The mechanisms of action
and further pharmacological … a case by case basis, with consideration of symptom severity, …

Basic pharmacological mechanisms and clinical evidence of the efficacy of Hochuekkito against infectious diseases and its potential for use against COVID‐19

S Takayama, A Kikuchi, T Makino… - Traditional & Kampo …, 2021 - Wiley Online Library
… the pneumonia caused by severe acute respiratory syndrome … cytokine release syndrome
in severe cases is characterized by … , which is often a problem in severe cases of COVID-19. …

[HTML][HTML] Molecular mechanisms and pharmacological interventions in the replication cycle of human coronaviruses

FM Simabuco, RE Tamura, ICB Pavan… - … and Molecular Biology, 2020 - SciELO Brasil
severe cases of pneumonia, has affected more than 23 million people worldwide until August
25 th , 2020. Here, we present a review of the cellular mechanisms … for pharmacological

Non-steroidal anti-inflammatory drugs, pharmacology, and COVID-19 infection

…, T Soeiro, AP Jonville-Bera, FS of Pharmacology - Therapies, 2020 - Elsevier
… analysis of complementary pharmacological data showed … of a severe bacterial complication,
in particular in the case of … the severity of bacterial infections through several mechanisms

Pharmacological approach for the reduction of inflammatory and prothrombotic hyperactive state in COVID-19 positive patients by acting on complement cascade

A Vitiello, R La Porta, V D'Aiuto, F Ferrara - Human Immunology, 2021 - Elsevier
… , most of the patients considered as severe cases have bilateral interstitial pneumonia and
a … The pathophysiology of COVID-19 infection and the mechanisms underlying the severe

Current pharmacological treatments for COVID‐19: What's next?

C Scavone, S Brusco, M Bertini… - … of pharmacology, 2020 - Wiley Online Library
cases, SARS-Cov-2 infection can cause fever, fatigue and dry cough, while severe cases
Since SARS-Cov-2 is still an unknown virus, we are now learning its transmission mechanisms

Azithromycin in COVID-19 patients: pharmacological mechanism, clinical evidence and prescribing guidelines

J Sultana, PM Cutroneo, S Crisafulli, G Puglisi… - Drug safety, 2020 - Springer
… One such case is the use of the macrolide azithromycin, … lung damage correlates with the
severity of viral infection; however… Moreover, for the treatment of severe bacterial CAP in COVID-…

Mechanisms of pain transmission and pharmacologic management

C Argoff - Current medical research and opinion, 2011 - Taylor & Francis
… NSAIDs may provide satisfactory analgesia as monotherapy for mild to moderate pain,
but they are primarily used as adjunct therapy in cases of severe painCitation11. …

SARS-CoV-2 and cardiovascular complications: From molecular mechanisms to pharmaceutical management

L Wu, AM O'Kane, H Peng, Y Bi, D Motriuk-Smith… - … pharmacology, 2020 - Elsevier
severe conditions develop acute respiratory distress syndrome (ARDS). Respiratory failure
caused by severe … In a recent study including 99 cases of COVID-19, the first fatality case was …