E Gavor, YK Choong, SY Er, H Sivaraman… - Trends in …, 2020 - cell.com
… acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and SARS-CoV, and discuss … rampant SARS-CoV-2 infections. We provide a perspective on the mechanisms of SARS-CoV-2-…
Y Ma, L Wu, N Shaw, Y Gao, J Wang… - Proceedings of the …, 2015 - National Acad Sciences
… The molecular basis of both these functions is unknown. Here, we describe crystal structures of severe acute respiratory syndrome (SARS)-CoV nsp14 in complex with its activator …
R Yan, Y Zhang, Y Li, L Xia, Y Guo, Q Zhou - Science, 2020 - science.org
… structuralbasis for the recognition of the SARS-CoV-2 by full-length human ACE2. This confirms that the novel virus SARS-CoV-… 2 (ACE2) as a receptor similar to SARS-CoV. Zhou et al …
… to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could accelerate vaccine design and drug discovery. We analyzed 294 anti–SARS-CoV-2 antibodies and found that …
M McCallum, N Czudnochowski, LE Rosen, SK Zepeda… - Science, 2022 - science.org
… This work defines the molecular basis for the broad evasion of humoral immunity exhibited by SARS-CoV-2 Omicron and underscores the SARS-CoV-2 S mutational plasticity as well as …
… -resolution structure of a ternary complex of SARS-CoV-2 … sugar of the first nucleotide of SARS-CoV-2 mRNA. We observe … (25 Å) ligand-binding site unique to SARS-CoV-2, which can …
Q Wang, J Wu, H Wang, Y Gao, Q Liu, A Mu, W Ji… - Cell, 2020 - cell.com
… molecular basis of SARS-CoV-2 RNA replication by determining the cryo-EM structures of … Compared with the apo complex, the structures show notable structural rearrangements …
… The SARS-CoV-2 RNA-dependent RNA polymerase … How the SARS-CoV-2 RTC discriminates between the … -TP), highlighting the structuralbasis for the selective incorporation of RDV-…