[PDF][PDF] Cytokine-targeted therapy in severely ill COVID-19 patients: options and cautions

M Rahmati, MA Moosavi - mortality, 2020 - researchgate.net
syndrome.[1, 2] Although, there is no specific antiviral therapy for COVID-19, understanding
of cytokine stormtherapeutic interventions.[3] Current reports have presented different …

Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology

R Channappanavar, S Perlman - Seminars in immunopathology, 2017 - Springer
… severe acute respiratory syndrome CoV (SARS-CoV) and Middle East respiratory syndrome
CoV (… Similarly, therapeutic interventions aimed towards reducing viral load were somewhat …

Potential treatments for COVID-19 related cytokine storm-beyond corticosteroids

Y Miao, L Fan, JY Li - Frontiers in immunology, 2020 - frontiersin.org
… As we know, the cytokine storm also occurs in … therapy, cytokine release syndrome (CRS)
occurs during and after the infusion of CAR T cells (8). In patients receiving CAR T cells therapy

High dose subcutaneous Anakinra to treat acute respiratory distress syndrome secondary to cytokine storm syndrome among severely ill COVID-19 patients

E Iglesias-Julian, M Lopez-Veloso… - Journal of …, 2020 - Elsevier
… Severely ill COVID-19 patients may end in acute respiratory distress syndrome (… as cytokine
storm syndrome (CSS). Inhibition of IL-1 by Anakinra (ANK) is a potential life-saving therapy

Are all cytokine storms the same?

N Panoskaltsis - Cancer Immunology, Immunotherapy, 2021 - Springer
… approach to cytokine storm is proposed for treatment and … secondary effects of cytokine
release syndrome which may be … cohort who suffered from TGN1412-induced cytokine storm. …

The role of MSC therapy in attenuating the damaging effects of the cytokine storm induced by COVID-19 on the heart and cardiovascular system

GM Ellison-Hughes, L Colley, KA O'Brien… - Frontiers in …, 2020 - frontiersin.org
syndrome (ARDS) appears to be a virally-induced over-activation or unregulated response of
the immune system, termed a “cytokine storm,” … Interventions that target single cytokines (ie, …

Is there a role for blood purification therapies targeting cytokine storm syndrome in critically severe COVID-19 patients?

G Chen, Y Zhou, J Ma, P Xia, Y Qin, X Li - Renal failure, 2020 - Taylor & Francis
syndromes (MODS) [Citation1,Citation8,Citation20]. These signs suggest that immune
disorders and cytokine storms … early CRRT intervention and ensure adequate treatment doses …

Cytokine storm induced by SARS-CoV-2

P Song, W Li, J Xie, Y Hou, C You - Clinica chimica acta, 2020 - Elsevier
… and even acute respiratory distress syndrome (ARDS) or … damage, and the therapeutic
interventions for preventing and … of IL-6 and has a therapeutic effect on cytokine storm caused …

Role of SARS-CoV-2-induced cytokine storm in multi-organ failure: Molecular pathways and potential therapeutic options

Y Nazerian, M Ghasemi, Y Yassaghi, A Nazerian… - International …, 2022 - Elsevier
… resulting from a condition called “cytokine storm” or “cytokine release syndrome” could have
a … about potential therapeutic targets and exciting interventions to control cytokine storm and …

Immune immunomodulation in coronavirus disease 2019 (COVID-19): strategic considerations for personalized therapeutic intervention

MW Hall, I Joshi, L Leal, EE Ooi - Clinical Infectious Diseases, 2022 - academic.oup.com
… There is leakage of proinflammatory cytokines such as IL-6, … and systemic levels of suppressive
cytokines such as IL-10 … cytokine levels is frequently referred to as a “cytokine storm,” the …