… There is an urgent need for definitive therapeuticintervention. Clinical reports indicate that the cytokinestorm associated with acute respiratory distress syndrome (ARDS) is the leading …
AKG Melo, KM Milby, ALMA Caparroz, ACPN Pinto… - PloS one, 2021 - journals.plos.org
… as important biomarkers of cytokinestormsyndrome. Elevated levels … and of those who require specific interventions or treatments. … but could also improve therapeutic decision making. …
… the development of cytokinestormsyndromes. Evidence for the … Further, a variety of potential therapeutic strategies that … to develop efficacious therapeuticinterventions for preventing …
Q Ye, B Wang, J Mao - Journal of infection, 2020 - Elsevier
… cytokinestorm and the options to inhibit the cytokinestorm, in … mainly applied in autoimmune diseases such as rheumatoid … These activities of ulinastatin promote the balance between …
M Cardone, M Yano, AS Rosenberg… - Frontiers in …, 2020 - frontiersin.org
… the intervention with the drugs listed in this review, we have grouped these therapeutics according … This cytokinestorm creates an inflammatory microenvironment in the tissue, already …
AA Rabaan, SH Al-Ahmed, J Muhammad, A Khan… - Vaccines, 2021 - mdpi.com
… the hyperinflammatory reactions in COVID-19 therapeuticinterventions [150,151]. Inhibition … with the hyperinflammatory syndrome/cytokinestorm. Therefore, therapeutic approaches for …
M Olbei, I Hautefort, D Modos, A Treveil… - Frontiers in …, 2021 - frontiersin.org
… help specialists identify interventions that alleviate CRS in different diseases and evaluate … treatment strategy for future cases. Recent reviews have attempted to compare diseases …
S Kang, T Kishimoto - Experimental & molecular medicine, 2021 - nature.com
… diseases, and we discuss the targeting IL-6 and/or IL-6R as a clinical therapeutic strategy for cytokinestorms. … without blocking the cytotoxic activities of engineered T cells directed …
JG Borrega, P Gödel, MA Rüger, ÖA Onur… - …, 2019 - journals.lww.com
… These toxicities require urgent diagnostic and therapeuticinterventions … diseases. Both conditions are characterized by a dysregulated immune response resulting in a cytokinestorm. …