[HTML][HTML] The 'cytokine storm': molecular mechanisms and therapeutic prospects

R Karki, TD Kanneganti - Trends in immunology, 2021 - cell.com
Cytokine storm syndrome (CSS) has generally been described as a collection of clinical
manifestations resulting from an overactivated immune system. Cytokine stormstherapeutic

Emerging aspects of cytokine storm in COVID-19: The role of proinflammatory cytokines and therapeutic prospects

R Dharra, AK Sharma, S Datta - Cytokine, 2023 - Elsevier
… SARS-CoV-2 mediated cytokine storm is associated with the mortality and morbidity of
COVID-19 patients. The key cytokines implicated in the onset of disease severity include TNF-α, …

Review on therapeutic targets for COVID-19: insights from cytokine storm

ML de Mélo Silva Júnior, LMA de Souza… - Postgraduate …, 2021 - academic.oup.com
… that release cytokines (notably IL-1, IL-6 and TNF) and … (cytokine storm) and tissue damage.
Some drugs have been studied as therapeutic targets (block to viral entry or to cytokine storm

[HTML][HTML] Immunoregulatory therapy strategies that target cytokine storms in patients with COVID‑19

X Wang, Z He, X Zhao - Experimental and Therapeutic …, 2021 - spandidos-publications.com
… Immunoregulatory therapies target the cytokine storms induced by severe acute respiratory
syndrome coronavirus 2 (SARS‑CoV‑2), the virus that causes COVID‑19, and include …

Cytokine storm and COVID-19: a chronicle of pro-inflammatory cytokines

A Fara, Z Mitrev, RA Rosalia, BM Assas - Open biology, 2020 - royalsocietypublishing.org
… prominent cytokinecytokine levels while discussing cytokine sources and biological
functions. Finally, we discuss in brief potential therapies attempting to modulate the cytokine storm. …

[HTML][HTML] The signal pathways and treatment of cytokine storm in COVID-19

L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - … and targeted therapy, 2021 - nature.com
cytokines are produced during the crosstalk between epithelial cells and immune cells in
COVID-19, which has linked the cytokine storm … In addition, the challenges and prospects in the …

[HTML][HTML] Cytokine storm in COVID-19: immunopathogenesis and therapy

C Zanza, T Romenskaya, AC Manetti, F Franceschi… - Medicina, 2022 - mdpi.com
… have tried to implement therapies to mitigate the cytokine storm in the treatment of COVID…
cytokine storms, analyzing its role in COVID-19 and providing a critical analysis of the therapies

The cytokine storm of COVID-19: a spotlight on prevention and protection

L Pearce, SM Davidson, DM Yellon - … Opinion on Therapeutic …, 2020 - Taylor & Francis
… Over-activity of chemotaxis triggers a macrophage activation syndrome (MAS) resulting
in the release of pro-inflammatory cytokines. IL-6 and TNF- α are at the forefront of hyper-…

Cytokine storm in COVID-19: An overview, mechanism, treatment strategies, and stem cell therapy perspective

NU Azmi, MU Puteri, D Lukmanto - … Sciences and Research, 2020 - scholarhub.ui.ac.id
… excessive amount of cytokine serum level (cytokine storm) has … Thus, the management of
the cytokine storm could be the … prospective treatment strategies for cytokine storm in COVID-19…

[PDF][PDF] Determining the disease outcome by cytokine storm during infectious diseases and targeting cytokines during sepsis: possible therapeutic options.

T Amin, A Hossain, FB Zahed - … and Experimental Therapeutics, 2022 - researchgate.net
… the major threat this cytokine storm-induced … the therapeutic interventions currently available
to treat sepsis to get an overview. We would also focus on the association of cytokine storm