M Zayed, K Iohara - Cell transplantation, 2020 - journals.sagepub.com
… The occurrence of a cytokinestorm in the lungs is a critical step in the disease pathogenesis… Currently, there is no effective treatment that targets the cytokinestorm and helps regenerate …
S Ramasamy, S Subbian - Clinical microbiology reviews, 2021 - Am Soc Microbiol
… -signaling and IFN therapy would favor the disease prognosis in COVID-19. This review … “cytokinestorm” induction and IFN antagonism during COVID-19 pathogenesis. Therapeutic …
… the exhaustive knowledge gathered on stem cells, COVID-19 infection, and cytokinestorm to develop new therapies based on stem cells. This gave us the inspiration to write this book. …
X Meng, Y Ling, L Zhang, Q Zhang, P Dong, T Zhu… - Bioscience …, 2020 - jstage.jst.go.jp
… inhibit cytokinestorms in patients with COVID-19 (10,11). The current article describes the pathogenesis of and relevant treatments for cytokinestorms … those storms in clinical practice. …
… The overproduction of pro-inflammatory cytokines (TNF, IL-6 and IL-1β) brings about what has been depicted as a cytokinestorm, prompting an expanded danger of vascular …
SS Nayak, A Naidu, SL Sudhakaran, S Vino… - Journal of personalized …, 2023 - mdpi.com
… prospects of multi-target QSAR models allowing us to choose lead compounds that affect multiple targets are very exciting, given that a cytokinestorm … in the cytokinestorm associated …
… We consider that a combined approach should be evaluated in which antiviral and immune modulatory drugs or inhibitors may show better prospects for reducing cytokinestorm severity…
SP Varahachalam, B Lahooti… - International journal …, 2021 - Taylor & Francis
… one or two cytokines might not be adequate to mitigate cytokinestorms and their ensuing … therapeutic approaches that target the essential immune cells that facilitate cytokinestorm …
ZX Zheng - World Journal of Clinical Cases, 2021 - ncbi.nlm.nih.gov
… COVID-19 can lead to a cytokinestorm and patients usually have early respiratory signs … Many clinical trials have proved that MSC therapy could be a potential feasible therapy for …