[HTML][HTML] Stem cell therapy: A promising treatment for COVID-19

ZX Zheng - World Journal of Clinical Cases, 2021 - ncbi.nlm.nih.gov
… COVID-19 can lead to a cytokine storm and patients usually have early respiratory signs …
Many clinical trials have proved that MSC therapy could be a potential feasible therapy for …

ZBP1-dependent inflammatory cell death, PANoptosis, and cytokine storm disrupt IFN therapeutic efficacy during coronavirus infection

R Karki, SJ Lee, R Mall, N Pandian, Y Wang… - Science …, 2022 - science.org
… in severe COVID-19 to ward off deleterious effects of type I IFNs including cytokine storm. …
Together, our results show that ZBP1 drives cell death, cytokine storm, and lethality in β-…

Tackling the cytokine storm using advanced drug delivery in allergic airway disease

VK Patel, S Vishwas, R Kumar, G De Rubis… - Journal of Drug Delivery …, 2023 - Elsevier
cytokines that triggers an uncontrolled aberrant inflammatory response known as ‘cytokine
storm’. This phenomenon interferes with the signalling and production of cytokines over time …

JAK-STAT signaling as an ARDS therapeutic target: Status and future trends

Y Zhang, Z Gao, F Jiang, H Yan, B Yang, Q He… - Biochemical …, 2023 - Elsevier
… Apoptosis of pulmonary epithelial further increases the release of inflammatory mediators
and creates a positive feedback of constant cytokine upregulation in the cytokine storm. …

T cell–directed therapies: lessons learned and future prospects

EH Liu, RM Siegel, DM Harlan, JJ O'Shea - Nature Immunology, 2007 - nature.com
… to avoid the problems of cytokine storm and autoimmunity. Cytokine storm is a particularly
… move forward with any new mAb T cell therapies. However, other experimental methods of …

Taming the cytokine storm: Biomechanical analysis of selective restriction of conformational interdomainal junctions of CD4 coreceptor in a sepsis model

E Abbas, D Mofed, TZ Salem - Medical Hypotheses, 2022 - Elsevier
… release of inflammatory cytokines leading to a cytokine storm. During the early priming phase
of the septic response; T-helper 1 (Th-1) secrete a distinct proinflammatory cytokine profile …

Emerging trends in COVID-19 treatment: learning from inflammatory conditions associated with cellular therapies

M Cancio, R Ciccocioppo, PRM Rocco, BL Levine… - Cytotherapy, 2020 - Elsevier
… Moreover, an imbalance between activated CD4 + T cells and regulatory T cells seem to
play a crucial role in triggering the cytokine storm. Notably, T. whipplei–specific T-helper 1 …

Complementary Pharmacological Treatment and Therapeutic Prospects for COVID-19

JA De Soto, F DSSc, ST Hakim, D Fouast - 2020 - osf.io
… with the cytokine storm that leads from pneumonia to ARDs. CONCLUSIONS: Developing
therapeutics interfering with the viral lifecycle, modulating the cytokine storm and protecting …

[PDF][PDF] Biochemical and immunological aspects of COVID-19 infection and therapeutical intervention of oral low dose cytokine therapy: a systematic review

M Ratheesh, S Sheethal, SP Jose, S Rajan… - Immunopharmacol …, 2021 - academia.edu
… an excessive generation of proinflammatory cytokines known as cytokine storm and also,
the … and effectiveness of oral low dose cytokines against the virus as a therapeutic approach. …

Harnessing self-assembled nanoplatform of Dexamethasone and α-linolenic acid for high-efficiency inhibition of pulmonary cytokine storm and fibrosis in mice

H Liu, M Ji, Y Qin, Y Sun, H Wang, P Xiao, J Zhao… - Nano Today, 2024 - Elsevier
… We hypothesized that the co-administration of Dex and LNA will effectively alleviate pulmonary
cytokine storms and fibrosis, thus contributing to efficient management of these diseases. …