… activation combined with an in-depth understanding of how they contribute to AD
pathology, it might provide more cues for development of therapeutic strategies in AD. …

… and NLRP3 inflammasome activation, and then developing related drugs may bring new
hope for treatment. At present, therapeutic strategies targeting NLRP3 inflammasome mainly …

NLRP3 inflammasome activation and IL-1β secretion have recently emerged as a central
mechanism in the pathogenesis of disease. Genetically defined syndromes like cryopyrin-…

… These findings suggest that novel therapeutic interventions at the molecular level might …
inhibition of NLRP3 inflammasome activation. Therefore, therapeutic strategies of inflammasome …

… therapeutic strategies for the clinical treatment of ischemic stroke. Understanding the NLRP3
inflammasome … in the NLRP3 pathway shows promise for ischemic stroke therapy. In this …

… pathway and the NLRP3 inflammasome. Understanding these negative regulatory mechanisms
should facilitate the development of much-needed therapeutic strategies for treatment of …

… of the relationship between the NLRP3 inflammasome, mitochondrial dysfunction, and … ,
therapeutic strategies to combat type 2 diabetes that target NLRP3 inflammasome and sirtuins …

… beyond NLRP3 inflammasome formation and activation, and discuss the role of the NLRP3
in … future therapeutic approaches targeting the NLRP3 inflammasome will be also discussed. …

… RNA interference has emerged as a promising therapeutic strategy that can provide durable
pharmacodynamic effects for several months with only a single dose. Efforts to leverage this …

… of NLRP3 inflammasome activation and its role in atherosclerosis. We also emphasize its
promising therapeutic … agents, may bring new therapeutic strategies with a reduced burden of …