Contribution of monocytes and macrophages to the local tissue inflammation and cytokine storm in COVID-19: Lessons from SARS and MERS, and potential …

A Jafarzadeh, P Chauhan, B Saha, S Jafarzadeh… - Life sciences, 2020 - Elsevier
… Both local tissue inflammation and cytokine storm play a key role in the development of …
to support viral dissemination, such as short lifespan and inability to establish viral replication. …

Fine tuning the cytokine storm by IFN and IL-10 following neurotropic coronavirus encephalomyelitis

C Savarin, CC Bergmann - Frontiers in immunology, 2018 - frontiersin.org
… Uncontrolled viral replication, extensive viral dissemination throughout the CNS, and …
Early viral replication also induces cytokines and chemokines, some of which are IFNα/β …

Cytokine storm—definition, causes, and implications

D Jarczak, A Nierhaus - International journal of molecular sciences, 2022 - mdpi.com
… production to fight systemic infection and dysregulated cytokine production. Disseminated
… Different viruses are associated with diverse patterns of cytokine release, but so far, this has …

The cytokine storm of COVID-19: a spotlight on prevention and protection

L Pearce, SM Davidson, DM Yellon - Expert Opinion on …, 2020 - Taylor & Francis
… target the COVID-19 induced cytokine storm. As this is not exclusive … Considering that
coagulopathy and disseminated intra-… Virus-induced cytokine storm is associated with Secondary …

Clinical features of cytokine storm syndrome

M Shimizu - Cytokine storm syndrome, 2019 - Springer
… the absence of overt disseminated intravascular coagulation (DIC… cases triggered by
respiratory viruses. Pulmonary infiltrates are … Furthermore, a patient with Epstein–Barr virus (EBV )-…

Cytokine storm induced by SARS-CoV-2

P Song, W Li, J Xie, Y Hou, C You - Clinica chimica acta, 2020 - Elsevier
… Therefore, using strategies to effectively suppress cytokine storm is … by which cytokine storm
is induced by the virus will be … The existence of disseminated intravascular coagulation is …

Cytokine storm syndrome in coronavirus disease 2019: A narrative review

YM Gao, G Xu, B Wang, BC Liu - Journal of internal medicine, 2021 - Wiley Online Library
virus, immune response and massive release of inflammatory factors eventually contribute to
a cytokine storm … systemic inflammatory responses, disseminated intravascular coagulation (…

The signal pathways and treatment of cytokine storm in COVID-19

L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - Signal transduction and …, 2021 - nature.com
… fever, capillary leak syndrome, disseminated intravascular coagulation, acute respiratory …
a given virus enhance the entry of not only that virus but also another serotype of the virus into …

Quantification of cytokine storms during virus infections

S Yuan, SC Jiang, ZW Zhang, YF Fu, J Hu… - Frontiers in …, 2021 - frontiersin.org
… , hepatitis B virus, hepatitis C virus, and enterovirus 71 were included in this analysis. …
cytokine fold change (FC), viral load, and clearance rate data from these highly pathogenic virus

Immune-mediated cytokine storm and its role in severe dengue

A Srikiatkhachorn, A Mathew, AL Rothman - Seminars in …, 2017 - Springer
cytokinescytokine response is not likely the cause of clinical symptoms but potentially
plays an important role in regulating local viral replication and dissemination by recruiting virus-…