A randomized clinical trial of combination chemotherapy with and without low‐molecular‐weight heparin in small cell lung cancer

M Altinbas, HS Coskun, O Er, M Ozkan… - … of thrombosis and …, 2004 - Wiley Online Library
Background Small cell lung cancer (SCLC) is a chemotherapy‐responsive tumor type but
most patients ultimately experience disease progression. SCLC is associated with …

Subcutaneous heparin treatment increases survival in small cell lung cancer

B Lebeau, C Chastang, JM Brechot, F Capron… - Cancer, 1994 - Wiley Online Library
Background. A positive influence of anticoagulant treatment in small cell lung cancer (SCLC)
has been sug gested by experimental and clinical data. Methods. In a multicenter clinical …

Randomized phase III trial of standard therapy plus low molecular weight heparin in patients with lung cancer: FRAGMATIC trial

F Macbeth, S Noble, J Evans, S Ahmed… - Journal of Clinical …, 2016 - ascopubs.org
Purpose Venous thromboembolism (VTE) is common in cancer patients. Evidence has
suggested that low molecular weight heparin (LMWH) might improve survival in patients with …

A randomized trial of anticoagulation with warfarin and of alternating chemotherapy in extensive small-cell lung cancer by the Cancer and Leukemia Group B.

AP Chahinian, KJ Propert, JH Ware… - Journal of Clinical …, 1989 - ascopubs.org
The Cancer and Leukemia Group B (CALGB) conducted a prospective randomized trial to
evaluate the role of warfarin and alternating chemotherapy in extensive small-cell lung …

Low-molecular-weight heparin in patients with advanced cancer: a phase 3 clinical trial

K Sideras, PL Schaefer, SH Okuno, JA Sloan… - Mayo Clinic …, 2006 - Elsevier
OBJECTIVE To prospectively assess whether low-molecular-weight heparin (LMWH)
provides a survival benefit in patients with advanced cancer. PATIENTS AND METHODS …

Warfarin versus low-molecular-weight heparin therapy in cancer patients

LR Zacharski, P Prandoni, M Monreal - The oncologist, 2005 - academic.oup.com
Abstract Learning Objectives After completing this course, the reader will be able to: Define
characteristics of the interface between deep vein thrombosis and malignancy. Evaluate …

[HTML][HTML] The effect of low‐molecular‐weight heparin on cancer survival. A systematic review and meta‐analysis of randomized trials

A Lazo‐Langner, GD Goss, JN Spaans… - Journal of Thrombosis …, 2007 - Elsevier
Background: Low‐molecular‐weight heparins (LMWH) have an antitumor effect in vitro and
in experimental animal models of malignancy. Retrospective data suggest that it might …

[HTML][HTML] The effect of low molecular weight heparin on survival in cancer patients: an updated systematic review and meta‐analysis of randomized trials

D Sanford, A Naidu, N Alizadeh… - Journal of Thrombosis and …, 2014 - Elsevier
Background Tumors may exploit the coagulation system to enhance the survival and
dissemination of cancer cells. Some studies have suggested that heparin and low molecular …

Randomized trial of chemotherapy and radiation therapy with or without warfarin for limited-stage small-cell lung cancer: a Cancer and Leukemia Group B study.

LH Maurer, JE Herndon 2nd, DR Hollis… - Journal of clinical …, 1997 - ascopubs.org
PURPOSE Studies by the Veterans Administration Cooperative Studies Program and
Cancer and Leukemia Group B (CALGB) suggested that the addition of warfarin to …

Anti-angiogenic therapy using thalidomide combined with chemotherapy in small cell lung cancer: a randomized, double-blind, placebo-controlled trial

SM Lee, PJ Woll, R Rudd, D Ferry… - Journal of the …, 2009 - academic.oup.com
Background Cancer cells rely on angiogenesis for growth and dissemination, and small cell
lung cancer (SCLC) is a highly angiogenic tumor. We evaluated thalidomide, an anti …