Frontal cortex neuron types categorically encode single decision variables

J Hirokawa, A Vaughan, P Masset, T Ott, A Kepecs - Nature, 2019 - nature.com
Individual neurons in many cortical regions have been found to encode specific, identifiable
features of the environment or body that pertain to the function of the region,–. However, in …

The importance of mixed selectivity in complex cognitive tasks

M Rigotti, O Barak, MR Warden, XJ Wang, ND Daw… - Nature, 2013 - nature.com
Single-neuron activity in the prefrontal cortex (PFC) is tuned to mixtures of multiple task-
related aspects. Such mixed selectivity is highly heterogeneous, seemingly disordered and …

Synaptic wiring motifs in posterior parietal cortex support decision-making

AT Kuan, G Bondanelli, LN Driscoll, J Han, M Kim… - Nature, 2024 - nature.com
The posterior parietal cortex exhibits choice-selective activity during perceptual decision-
making tasks,,,,,,,,–. However, it is not known how this selective activity arises from the …

Frontal neurons driving competitive behaviour and ecology of social groups

SW Li, O Zeliger, L Strahs, R Báez-Mendoza… - Nature, 2022 - nature.com
Competitive interactions have a vital role in the ecology of most animal species,–and
powerfully influence the behaviour of groups,. To succeed, individuals must exert effort …

[HTML][HTML] Mouse prefrontal cortex represents learned rules for categorization

S Reinert, M Hübener, T Bonhoeffer, PM Goltstein - Nature, 2021 - nature.com
The ability to categorize sensory stimuli is crucial for an animal's survival in a complex
environment. Memorizing categories instead of individual exemplars enables greater …

Neurons in the orbitofrontal cortex encode economic value

C Padoa-Schioppa, JA Assad - Nature, 2006 - nature.com
Economic choice is the behaviour observed when individuals select one among many
available options. There is no intrinsically 'correct'answer: economic choice depends on …

Context-dependent computation by recurrent dynamics in prefrontal cortex

V Mante, D Sussillo, KV Shenoy, WT Newsome - nature, 2013 - nature.com
Prefrontal cortex is thought to have a fundamental role in flexible, context-dependent
behaviour, but the exact nature of the computations underlying this role remains largely …

Distributed coding of choice, action and engagement across the mouse brain

NA Steinmetz, P Zatka-Haas, M Carandini, KD Harris - Nature, 2019 - nature.com
Vision, choice, action and behavioural engagement arise from neuronal activity that may be
distributed across brain regions. Here we delineate the spatial distribution of neurons …

Distinct relationships of parietal and prefrontal cortices to evidence accumulation

TD Hanks, CD Kopec, BW Brunton, CA Duan, JC Erlich… - Nature, 2015 - nature.com
Gradual accumulation of evidence is thought to be fundamental for decision-making, and its
neural correlates have been found in several brain regions,,,,,,,. Here we develop a …

Cortical substrates for exploratory decisions in humans

ND Daw, JP O'doherty, P Dayan, B Seymour, RJ Dolan - Nature, 2006 - nature.com
Decision making in an uncertain environment poses a conflict between the opposing
demands of gathering and exploiting information. In a classic illustration of this 'exploration …