Decision-related activity in sensory neurons reflects more than a neuron's causal effect

H Nienborg, BG Cumming - Nature, 2009 - nature.com
During perceptual decisions, the activity of sensory neurons correlates with a subject's
percept, even when the physical stimulus is identical,,,,,,,,. The origin of this correlation is …

A neuro-computational model of economic decisions

A Rustichini, C Padoa-Schioppa - Journal of …, 2015 - journals.physiology.org
Neuronal recordings and lesion studies indicate that key aspects of economic decisions take
place in the orbitofrontal cortex (OFC). Previous work identified in this area three groups of …

Neuron-type-specific signals for reward and punishment in the ventral tegmental area

JY Cohen, S Haesler, L Vong, BB Lowell, N Uchida - nature, 2012 - nature.com
Dopamine has a central role in motivation and reward. Dopaminergic neurons in the ventral
tegmental area (VTA) signal the discrepancy between expected and actual rewards (that is …

Synaptic wiring motifs in posterior parietal cortex support decision-making

AT Kuan, G Bondanelli, LN Driscoll, J Han, M Kim… - Nature, 2024 - nature.com
The posterior parietal cortex exhibits choice-selective activity during perceptual decision-
making tasks,,,,,,,,–. However, it is not known how this selective activity arises from the …

Neurobiology of economic choice: a good-based model

C Padoa-Schioppa - Annual review of neuroscience, 2011 - annualreviews.org
Traditionally the object of economic theory and experimental psychology, economic choice
recently became a lively research focus in systems neuroscience. Here I summarize the …

Probabilistic reasoning by neurons

T Yang, MN Shadlen - Nature, 2007 - nature.com
Our brains allow us to reason about alternatives and to make choices that are likely to pay
off. Often there is no one correct answer, but instead one that is favoured simply because it is …

Prefrontal cortex output circuits guide reward seeking through divergent cue encoding

JM Otis, VMK Namboodiri, AM Matan, ES Voets… - Nature, 2017 - nature.com
The prefrontal cortex is a critical neuroanatomical hub for controlling motivated behaviours
across mammalian species,,. In addition to intra-cortical connectivity, prefrontal projection …

Neural correlates, computation and behavioural impact of decision confidence

A Kepecs, N Uchida, HA Zariwala, ZF Mainen - Nature, 2008 - nature.com
Humans and other animals must often make decisions on the basis of imperfect evidence,.
Statisticians use measures such as P values to assign degrees of confidence to …

A dynamic code for economic object valuation in prefrontal cortex neurons

KI Tsutsui, F Grabenhorst, S Kobayashi… - Nature …, 2016 - nature.com
Neuronal reward valuations provide the physiological basis for economic behaviour. Yet,
how such valuations are converted to economic decisions remains unclear. Here we show …

A general mechanism for perceptual decision-making in the human brain

HR Heekeren, S Marrett, PA Bandettini, LG Ungerleider - Nature, 2004 - nature.com
Findings from single-cell recording studies suggest that a comparison of the outputs of
different pools of selectively tuned lower-level sensory neurons may be a general …