The neuronal logic of how internal states control food choice

D Münch, D Goldschmidt, C Ribeiro - Nature, 2022 - nature.com
When deciding what to eat, animals evaluate sensory information about food quality
alongside multiple ongoing internal states,,,,,,,,–. How internal states interact to alter …

Two types of dopamine neuron distinctly convey positive and negative motivational signals

M Matsumoto, O Hikosaka - Nature, 2009 - nature.com
Midbrain dopamine neurons are activated by reward or sensory stimuli predicting reward,,,.
These excitatory responses increase as the reward value increases. This response property …

Choosing the greater of two goods: neural currencies for valuation and decision making

LP Sugrue, GS Corrado, WT Newsome - Nature Reviews Neuroscience, 2005 - nature.com
To make adaptive decisions, animals must evaluate the costs and benefits of available
options. The nascent field of neuroeconomics has set itself the ambitious goal of …

Distributed coding of choice, action and engagement across the mouse brain

NA Steinmetz, P Zatka-Haas, M Carandini, KD Harris - Nature, 2019 - nature.com
Vision, choice, action and behavioural engagement arise from neuronal activity that may be
distributed across brain regions. Here we delineate the spatial distribution of neurons …

The primate amygdala represents the positive and negative value of visual stimuli during learning

JJ Paton, MA Belova, SE Morrison, CD Salzman - Nature, 2006 - nature.com
Visual stimuli can acquire positive or negative value through their association with rewards
and punishments, a process called reinforcement learning. Although we now know a great …

Elucidating the underlying components of food valuation in the human orbitofrontal cortex

S Suzuki, L Cross, JP O'Doherty - Nature neuroscience, 2017 - nature.com
The valuation of food is a fundamental component of our decision-making. Yet little is known
about how value signals for food and other rewards are constructed by the brain. Using a …

Specialized coding of sensory, motor and cognitive variables in VTA dopamine neurons

B Engelhard, J Finkelstein, J Cox, W Fleming, HJ Jang… - Nature, 2019 - nature.com
There is increased appreciation that dopamine neurons in the midbrain respond not only to
reward and reward-predicting cues,, but also to other variables such as the distance to …

Prefrontal mechanisms of behavioral flexibility, emotion regulation and value updating

PH Rudebeck, RC Saunders, AT Prescott… - Nature …, 2013 - nature.com
Two ideas have dominated neuropsychology concerning the orbitofrontal cortex (OFC). One
holds that OFC regulates emotion and enhances behavioral flexibility through inhibitory …

Free choice activates a decision circuit between frontal and parietal cortex

B Pesaran, MJ Nelson, RA Andersen - Nature, 2008 - nature.com
We often face alternatives that we are free to choose between. Planning movements to
select an alternative involves several areas in frontal and parietal cortex,,,,,,,,,, that are …

The root of all value: a neural common currency for choice

DJ Levy, PW Glimcher - Current opinion in neurobiology, 2012 - Elsevier
How do humans make choices between different types of rewards? Economists have long
argued on theoretical grounds that humans typically make these choices as if the values of …