Method and apparatus for imaging unsectioned tissue specimens

JG Fujimoto, MG Giacomelli, T Yoshitake… - US Patent …, 2019 - Google Patents
An apparatus and method for real-time optical imaging of a tissue specimen. The apparatus
comprises a primary imaging system configured to use an illumination source to acquire …

Speckle reduction in optical coherence tomography by path length encoded angular compounding

GJ Tearney, N Iftimia, BE Bouma - US Patent 8,174,702, 2012 - Google Patents
Speckle, a factor reducing image quality in optical coherence tomography (“OCT”), can limit
the ability to identify cellular structures that are important for the diagnosis of a variety of …

Optical imaging system with direct image construction

X Cheng, X Xu, S Zhou, L Wang, M Wang… - US Patent App. 09 …, 2002 - Google Patents
The invention generally relates to optical imaging systems and methods for providing
images of two-dimensional or three-dimensional spatial or temporal distribution of properties …

Arrangement, method and computer-accessible medium for identifying characteristics of at least a portion of a blood vessel contained within a tissue using spectral …

G Tearney, B Bouma - US Patent App. 11/687,112, 2007 - Google Patents
An apparatus, method and computer-accessible medium for identifying characteristics of at
least a portion of a blood vessel contained within a tissue can be provided. For example, it is …

Systems, methods and computer-accessible medium which provide microscopic images of at least one anatomical structure at a particular resolution

GJ Tearney, BE Bouma, JA Gardecki, L Liu - US Patent 8,896,838, 2014 - Google Patents
Exemplary embodiments of probes, apparatus, systems and methods can be provided which
provide at least one electro-magnetic radiation to at least one sample. For example, a …

Apparatus and method for obtaining and providing imaging information associated with at least one portion of a sample, and effecting such portion (s)

GJ Tearney, BE Bouma, D Yelin - US Patent 8,838,213, 2014 - Google Patents
Exemplary apparatus and process can be provided for imaging information associated with
at least one portion of a sample. For example,(i) at least two first different wavelengths of at …

System, method and apparatus for optical imaging of luminal organs, and for centering within and contacting a luminal organ

MJ Gora, G Dierksen, BE Bouma… - US Patent App. 13 …, 2013 - Google Patents
Exemplary apparatus and method can be provided for obtaining data for at least one portion
within at least one luminal or hollow sample. It is possible, eg, using a first optical …

Methods and systems for detecting abnormal tissue using spectroscopic techniques

DW Hochman - US Patent 6,671,540, 2003 - Google Patents
(56) References Cited(57) ABSTRACT US PATENT DOCUMENTS The present invention
provides methods and Systems for 4,223,680 A 9/1980 Jöbsis........................ 128/633 …

Systems and methods for tomographic image reconstruction

BW Pogue, D Piao, KD Paulsen, S Jiang… - US Patent …, 2011 - Google Patents
Optical tomography systems that provide light of multiple distinct wavelengths from a
plurality of Sources are described. The systems direct light into mammalian tissue, and light …

Apparatus, method and system for performing phase-resolved optical frequency domain imaging

GJ Tearney, BE Bouma, JF De Boer, BJ Vakoc… - US Patent …, 2015 - Google Patents
Apparatus, system and method are provided which utilize signals received from a reference
and a sample. In particular, a radiation is provided which includes at least one first electro …