The Tip60 histone acetyltransferase is part of an evolutionarily conserved multisubunit
complex, NuA4, which is recruited by many transcription factors to their target promoters …

TIP60 was originally identified as a cellular acetyltransferase protein that interacts with HIV-1
Tat. As a consequence, the role of TIP60 in transcriptional regulation has been investigated …

The histone acetyl transferase Tip60 (HTATIP) belongs to a multimolecular complex
involved in the cellular response to DNA damage. Tip60 participates in cell cycle arrest …

The histone acetyltransferase TIP60 regulates the DNA damage response following
genotoxic stress by acetylating histone and remodeling chromatin. However, the molecular …

The histone acetyl transferase Tip60 (HTATIP) shares many properties with the tumor
suppressor p53 (TP53). Both proteins are involved in the cellular response to DNA damage …

DNA double-strand break (DSB) repair involves complex interactions between chromatin
and repair proteins, including Tip60, a tumour suppressor. Tip60 is an acetyltransferase that …

The Tip60 histone acetyltransferase belongs to a multimolecular complex that contains
many chromatin remodeling enzymes including the ATPase p400, a protein involved in …

The NuA4/TIP60 acetyltransferase complex is a key regulator of genome expression and
stability. Here we identified MBTD1 as a stable subunit of the complex, and we reveal that …

Tip60 (Tat-interactiveprotein, 60 kDa), a cellular protein with intrinsic histone
acetyltransferase activity, is involved in DNA damage repair and apoptosis. Recent studies …

Tip60 is an essential acetyltransferase required for acetylation of nucleosomal histones and
other nonhistone proteins. Tip60 acetylates the p53 tumor suppressor at lysine 120 (K120) …