Seasonal malaria vaccination: protocol of a phase 3 trial of seasonal vaccination with the RTS, S/AS01E vaccine, seasonal malaria chemoprevention and the …

D Chandramohan, A Dicko, I Zongo, I Sagara… - BMJ open, 2020 - bmjopen.bmj.com
Introduction Seasonal malaria chemoprevention (SMC), with sulphadoxine–pyrimethamine
plus amodiaquine (SP+ AQ) is effective but does not provide complete protection against …

Decision-making on malaria vaccine introduction: the role of cost-effectiveness analyses

VS Moorthy, R Hutubessy… - Bulletin of the World …, 2012 - SciELO Public Health
• What is the evidence that RTS, S/AS01 vaccination is not associated with serious adverse
reactions in children aged less than 17 months?• What level of protection against clinical …

Statistical methodology for the evaluation of vaccine efficacy in a phase III multi-centre trial of the RTS, S/AS01 malaria vaccine in African children

M Lievens, JJ Aponte, J Williamson, B Mmbando… - Malaria journal, 2011 - Springer
Background There has been much debate about the appropriate statistical methodology for
the evaluation of malaria field studies and the challenges in interpreting data arising from …

The bumpy road to malaria vaccination

C Willyard - Nature, 2022 - nature.com
S48| Nature| Vol 612| 22/29 December 2022| Corrected 19 January 2023© 2022 Springer
Nature Li mited. All rights reserved. efficacy of medicines and vaccines destined for low-and …

Efficacy of RTS, S/AS01E vaccine against malaria in children 5 to 17 months of age

P Bejon, J Lusingu, A Olotu, A Leach… - … England Journal of …, 2008 - Mass Medical Soc
Background Plasmodium falciparum malaria is a pressing global health problem. A previous
study of the malaria vaccine RTS, S (which targets the circumsporozoite protein), given with …

PA-711 Assessment of effectiveness of the RTS, S/AS01 malaria vaccine using the case-control approach: lessons learned from malaria vaccine pilot evaluation …

T Gyan, S Akech, DP Mathanga, T Kwambai, C Stanley… - 2023 - gh.bmj.com
Background The RTS, S/AS01 malaria vaccine was introduced in Ghana, Kenya, and
Malawi in 2019. Evaluation includes case-control studies designed to monitor individual …

Safety of the Malaria Vaccine Candidate, RTS,S/AS01E in 5 to 17 Month Old Kenyan and Tanzanian Children

J Lusingu, A Olotu, A Leach, M Lievens, J Vekemans… - PLoS …, 2010 - journals.plos.org
The malaria vaccine candidate, RTS, S/AS01E, showed promising protective efficacy in a
trial of Kenyan and Tanzanian children aged 5 to 17 months. Here we report on the …

Efficacy of the RTS, S/AS02A vaccine against Plasmodium falciparum infection and disease in young African children: randomised controlled trial

PL Alonso, J Sacarlal, JJ Aponte, A Leach, E Macete… - The Lancet, 2004 - thelancet.com
Background Development of an effective malaria vaccine could greatly contribute to disease
control. RTS, S/AS02A is a pre-erythrocytic vaccine candidate based on Plasmodium …

RTS, S/AS01 malaria vaccine and child mortality

O Müller, Y Tozan, H Becher - The Lancet, 2015 - thelancet.com
89: 233–35. 5 Aaby P, Jensen H, Samb B, et al. Differences in female-male mortality after
high-titre measles vaccine and association with subsequent vaccination with diphtheria …

WHO's malaria vaccine study represents a “serious breach of international ethical standards”

P Doshi - bmj, 2020 - bmj.com
WHO’s malaria vaccine study represents a “serious breach of international ethical standards” |
The BMJ Skip to main content Intended for healthcare professionals Access provided by Google …