Efficacy of RTS, S/AS01E malaria vaccine and exploratory analysis on anti-circumsporozoite antibody titres and protection in children aged 5–17 months in Kenya and …

A Olotu, J Lusingu, A Leach, M Lievens… - The Lancet infectious …, 2011 - thelancet.com
Summary Background RTS, S/AS01E is the lead candidate malaria vaccine. We recently
showed efficacy against clinical falciparum malaria in 5–17 month old children, during an …

Safety, Immunogenicity and Duration of Protection of the RTS,S/AS02D Malaria Vaccine: One Year Follow-Up of a Randomized Controlled Phase I/IIb Trial

P Aide, JJ Aponte, M Renom, T Nhampossa… - PLoS …, 2010 - journals.plos.org
Background The RTS, S/AS02D vaccine has been shown to have a promising safety profile,
to be immunogenic and to confer protection against malaria in children and infants. Methods …

Randomized Controlled Trial of RTS,S/AS02D and RTS,S/AS01E Malaria Candidate Vaccines Given According to Different Schedules in Ghanaian Children

S Owusu-Agyei, D Ansong, K Asante… - PLoS …, 2009 - journals.plos.org
Background The target delivery channel of RTS, S candidate malaria vaccines in malaria-
endemic countries in Africa is the World Health Organisation Expanded Program on …

Seasonal vaccination with RTS, S/AS01E vaccine with or without seasonal malaria chemoprevention in children up to the age of 5 years in Burkina Faso and Mali: a …

A Dicko, JB Ouedraogo, I Zongo, I Sagara… - The Lancet Infectious …, 2024 - thelancet.com
Background Seasonal vaccination with the RTS, S/AS01 E vaccine combined with seasonal
malaria chemoprevention (SMC) prevented malaria in young children more effectively than …

Safety and immunogenicity of RTS, S/AS02D malaria vaccine in infants

S Abdulla, R Oberholzer, O Juma… - … England Journal of …, 2008 - Mass Medical Soc
Background The RTS, S/AS malaria vaccine is being developed for delivery through the
World Health Organization's Expanded Program on Immunization (EPI). We assessed the …

RTS, S/AS01 malaria vaccine pilot implementation in western Kenya: a qualitative longitudinal study to understand immunisation barriers and optimise uptake

J Hoyt, G Okello, T Bange, S Kariuki, MF Jalloh… - BMC Public Health, 2023 - Springer
Background Malaria is a significant public health threat in sub-Saharan Africa, particularly
among children. The RTS, S/AS01 malaria vaccine reduces the risk and severity of malaria …

The public health impact of malaria vaccine RTS, S in malaria endemic Africa: country-specific predictions using 18 month follow-up Phase III data and simulation …

MA Penny, K Galactionova, M Tarantino, M Tanner… - BMC medicine, 2015 - Springer
Abstract Background The RTS, S/AS01 malaria vaccine candidate recently completed
Phase III trials in 11 African sites. Recommendations for its deployment will partly depend on …

Malaria vaccines

SL Hoffman, JE Epstein - Essential Malariology, 4Ed, 2017 - taylorfrancis.com
Many malariologists believe that different types of malaria vaccines may be necessary for
different populations. Whether or not this turns out to be the case, we find it useful to think …

Immunogenicity of the RTS, S/AS01 malaria vaccine and implications for duration of vaccine efficacy: secondary analysis of data from a phase 3 randomised …

MT White, R Verity, JT Griffin, KP Asante… - The Lancet infectious …, 2015 - thelancet.com
Summary Background The RTS, S/AS01 malaria vaccine targets the circumsporozoite
protein, inducing antibodies associated with the prevention of Plasmodium falciparum …

Malaria vaccines

GV Brown, JC Reeder - The Medical Journal of Australia, 2002 - mja.com.au
Malaria remains a global crisis that kills at least one to two million people per year, mainly
children in sub-Saharan Africa. 1 Forty per cent of the world's population is at risk of malaria …