[HTML][HTML] The RTS, S malaria vaccine: Journey from conception to recommendation

OM Egbewande - Public Health in Practice, 2022 - Elsevier
The RTS, S malaria vaccine was recently recommended for use among children at risk in
malaria endemic regions. Although significant efforts have been made to minimise malaria …

The development of the RTS, S malaria vaccine candidate: challenges and lessons

WR Ballou - Parasite immunology, 2009 - Wiley Online Library
RTS, S is the world's most advanced malaria vaccine candidate and is intended to protect
infants and young children living in malaria endemic areas of sub‐Saharan Africa against …

[HTML][HTML] First results of phase 3 trial of RTS, S/AS01 malaria vaccine in African children

RTS, S Clinical Trials Partnership - New England Journal of …, 2011 - Mass Medical Soc
Background An ongoing phase 3 study of the efficacy, safety, and immunogenicity of
candidate malaria vaccine RTS, S/AS01 is being conducted in seven African countries …

The RTS, S/AS01 malaria vaccine in children aged 5-17 months at first vaccination

P Vandoolaeghe, L Schuerman - The Pan African Medical Journal, 2018 - europepmc.org
Résumé Le vaccin antipaludique RTS, S/AS01 a reçu un avis scientifique favorable de
l'Agence Européenne des Médicaments (EMA) en Juillet 2015. L'Organisation Mondiale de …

The RTS, S malaria vaccine

S Casares, TD Brumeanu, TL Richie - Vaccine, 2010 - Elsevier
RTS, S is the most advanced candidate vaccine against human malaria. During its
remarkable journey from conception and design in the early 1980s to the multicenter Phase …

Design of a phase III multicenter trial to evaluate the efficacy of the RTS, S/AS01 malaria vaccine in children across diverse transmission settings in Africa

A Leach, J Vekemans, M Lievens, O Ofori-Anyinam… - Malaria journal, 2011 - Springer
Abstract Background GlaxoSmithKline Biologicals and the PATH Malaria Vaccine Initiative
are working in partnership to develop a malaria vaccine to protect infants and children living …

[PDF][PDF] Malaria vaccine: WHO position paper–January 2016

S Agnandji - N Engl J Med, 2011 - cdn.who.int
BACKGROUND: An ongoing phase 3 study of the efficacy, safety, and immunogenicity of
candidate malaria vaccine RTS, S/AS01 is being conducted in seven African countries …

Malaria vaccine approval: A step change for global health

A Gumulira - N. Engl. J. Med, 2021 - thelancet.com
On Oct 6, WHO announced that it will be recommending widespread use of the RTS, S/AS01
(RTS, S) malaria vaccine for children in sub-Saharan Africa and in other regions with …

Phase 3 trial with the RTS, S/AS01 malaria vaccine shows protection against clinical and severe malaria in infants and children in Africa

G Targett - BMJ Evidence-Based Medicine, 2015 - ebm.bmj.com
Methods This was a phase 3 double-blind trial of the RTS, S/AS01 vaccine which is directed
against the pre-erythrocytic stage of Plasmodium falciparum malaria. It was conducted in 11 …

First proven malaria vaccine rolled out in Africa--but doubts linger

A Maxmen - Nature, 2019 - go.gale.com
First proven malaria vaccine rolled out in Africa -- but doubts linger - Document - Gale
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