Trial starts of malaria vaccine in 2000 children in Mozambique

A Gulland - BMJ, 2003 - bmj.com
Pedro Alonso, head of the Centre for International Health at the University of Barcelona,
Spain, and principal investigator of the vaccine trial, told a press conference earlier this …

Malaria vaccine becomes first to achieve 75% efficacy goal in trial of children

E Mahase - BMJ: British Medical Journal (Online), 2021 - search.proquest.com
A vaccine candidate for malaria has become the first to meet the World Health
Organization's 75% efficacy target, after a trial in 450 children reported 77% efficacy. 1 The …

Trial shows vaccine halves malaria episodes in children in Africa

JH Tanne - 2011 - bmj.com
An antimalaria vaccine halved the number of first clinical episodes of malaria and severe
malaria in children in the 12 months after vaccination, according to results from a clinical …

Candidate malaria vaccine becomes less effective over time, study shows

J Wise - BMJ, 2013 - bmj.com
A candidate vaccine against malaria has been shown to almost halve the number of malaria
cases in young children but only to reduce cases by a quarter in infants. The effectiveness of …

WHO hails “historic day” as it recommends malaria vaccine

J Wise - 2021 - bmj.com
The World Health Organization has recommended widespread use of the RTS, S malaria
vaccine among children in sub-Saharan Africa and other areas with moderate to high …

WHO recommends second vaccine for malaria prevention in children

E Mahase - 2023 - bmj.com
“This second vaccine holds real potential to close the huge demand-and-supply gap,” said
WHO's regional director for Africa, Matshidiso Moeti.“Delivered to scale and rolled out …

Malaria vaccine is partly effective in young children, study shows

S Mayor - BMJ, 2015 - bmj.com
The study included 6537 infants aged 6-12 weeks and 8922 children aged 5-17 months who
were enrolled at 11 centres in seven countries across sub-Saharan Africa. They were …

Promise of new malaria vaccines

PJ Hotez, M Matshaba - bmj, 2022 - bmj.com
Throughout the covid-19 pandemic, global health scientists and professionals worried not
only about this new and emerging viral infection but also about a potential diversion of …

Malaria vaccine difficult to roll out because four doses are needed, WHO says

A Gulland - 2015 - bmj.com
A phase III trial showed that the RTS, S vaccine, which acts against Plasmodium falciparum,
had an efficacy of around 30%. 1 The vaccine, which is most effective in children aged …

Malaria vaccine trial shows lower efficacy in younger than in older infants

A Gulland - 2012 - bmj.com
The efficacy of the vaccine RTS, S/AS01 in infants aged 6-12 weeks against clinical and
severe malaria was 31% and 37%, respectively, found the study, published in the New …