To search for leads against malaria, compounds from the Cameroon Natural Product Library
(CANAPL), were screened by molecular docking studies against the enzyme target …

Malaria is one of the diseases for which even today not many suitable drugs are available.
The rapid spread of resistance toward current drugs encourages the study for new active …

Marine natural products (MNPs) have been an important and rich source for antimicrobial
drug discovery and an effective alternative to control drug resistant infections. Herein, we …

In an attempt to synthesize carvotacetone analogues, new 3-O-benzyl-carvotacetone (10)
and previously reported 3-hydroxy-2-isopropyl-5-methyl-p-benzoquinone (11) were …

Bioassay-guided fractionation of an extract of Carpha glomerata (Cyperaceae) led to the
isolation of seven compounds. Compounds 1 (carphorin A), 3 (carphorin C), 4 (carphorin D) …

Four new meroterpenes, alisiaquinones A− C (1− 3) and alisiaquinol (4), were isolated from
a New Caledonian deep water sponge. Their structures and relative stereochemistry were …

Schiff bases of isatin were synthesized by reacting isatin with substituted aromatic amines
and were characterized by UV-Visible, 1HNMR, 13CNMR, IR and micro analytical data. All …

The CH2Cl2-MeOH (1: 1) extract of the aerial parts of Sphaeranthus bullatus, an annual
herb native to tropical East Africa, showed activity against chloroquine sensitive D6 (IC50 …

Based on a survey of remedies used in Renaissance Europe to treat malaria, we prepared
and screened a library of 254 extracts from 61 plants for antiplasmodial activity in vitro …

Malaria is a global problem affecting a large population without any demarcation between
developed and developing world communities. The already approved compounds for the …