In the course of our continuing efforts to identify bioactive secondary metabolites from Red
Sea marine invertebrates, we have investigated the sponge Hemimycale arabica. The …

Marine sponge is a marine life that enrich with natural resources which is significant in
medical development. Most of these are secondary metabolites produced by sponge used …

The growing drug resistance of Plasmodia spp. to current antimalarial agents in the quinine
and artemisinin families further asserts the need for novel drug classes to combat malaria …

Pure natural monoterpenes were evaluated in vitro for their antiplasmodial activities against
Plasmodium falciparum. Chemically modified terpenes were also tested to see whether the …

The antimalarial activity of the raw petroleum ether and dichloromethane extracts of the
stems of Parinari capensis (Chrysobalanceae) was determined. Phytochemical investigation …

The syntheses and antiplasmodial activities of various substituted aminoquinolines coupled
to an adamantane carrier are described. The compounds exhibited pronounced in vitro and …

The difficulty of obtaining an antimalarial vaccine along traditional lines, because of the
highly adaptive character of the malaria parasite, prompts a ceaseless need for new drugs …

A new, improved-throughput lipid-water interface assay was developed in which the
inhibition of β-haematin formation by diverse inhibitors was investigated. Monopalmitoyl-rac …

Based on the existing reports on the bioactive isatin derivatives, a number of Schiff bases
were synthesized by reacting 5-substituted isatins with bioactive amines/hydrazides and …

Medicinal plants have historically proven their value as sources of molecules with
therapeutic potential, and nowadays still represent an interesting pool for the discovery of …