In the era of resistance to the available antimalarial drugs, the discovery of antiplasmodial
compounds with novel mechanism of action is needed. In this regard, plants with …

In the course of our continuing efforts to identify bioactive secondary metabolites from Red
Sea marine sponges, we have investigated the sponge Hemimycale sp. The cytotoxic …

Sarcophine (1) is a furanocembranoid diterpene first reported from the Red Sea soft coral
Sarcophyton glaucum with remarkable yields of up to 3% dry weight. Semisynthetic …

Malaria is still one of the most destructive parasitic infections in several tropical and
subtropical countries. Natural products have played a dominant role in the discovery of lead …

Bioactivity-guided separation of the methanol extract of Calophyllum scriblitifolium bark led
to the isolation of five new pyranocoumarins, caloforines A–E (1–5) and two new coumarins …

Stationary and slow-moving marine organisms regularly employ a natural product chemical
defense to prevent being colonized by marine micro-and macroorganisms. While these …

Novel drug leads for malaria therapy are urgently needed because of the widespread
emergence of resistance to all available drugs. Screening of the Harbor Branch enriched …

Four new bibenzyls, bauhinols A–D (1–4), together with the two known bibenzyls 5 and 6,
were isolated from the roots of Bauhinia saccocalyx, and their structures were elucidated by …

Cystic echinococcosis (CE) is a significant global public health concern, particularly in
regions where livestock rearing is prevalent. Despite its impact on morbidity and mortality …

The triterpenes balsaminoside B (1) and karavilagenin C (2) were isolated from the African
medicinal plant Momordica balsamina L. Karavoates B (3) and D (4) were synthesized by …