Identification of intracellular signaling cascades mediating the PACAP-induced increase in guinea pig cardiac neuron excitability
JD Tompkins, RL Parsons - Journal of molecular neuroscience, 2008 - Springer
The pituitary adenylate cyclase-activating polypeptide (PACAP) increases excitability of
guinea pig cardiac neurons, an effect mediated through activation of PAC 1 receptors. The …
guinea pig cardiac neurons, an effect mediated through activation of PAC 1 receptors. The …
PACAP type I receptor transactivation is essential for IGF‐1 receptor signalling and antiapoptotic activity in neurons
N Delcourt, E Thouvenot, B Chanrion, N Galéotti… - The EMBO …, 2007 - embopress.org
Insulin‐like growth factor‐1 (IGF‐1) and pituitary adenylyl cyclase activating polypeptide
(PACAP) are both potent neurotrophic and antiapoptotic factors, which exert their effects via …
(PACAP) are both potent neurotrophic and antiapoptotic factors, which exert their effects via …
PAC1-expressing structures of neural retina alter their PAC1 isoform splicing during postnatal development
Pituitary adenylate cyclase-activating polypeptide (PACAP), a member of the
secretin/glucagon/vasoactive intestinal peptide family, exerts various effects on neuronal …
secretin/glucagon/vasoactive intestinal peptide family, exerts various effects on neuronal …
Nickel suppresses the PACAP-induced increase in guinea pig cardiac neuron excitability
JD Tompkins, LA Merriam, BM Girard… - … of Physiology-Cell …, 2015 - journals.physiology.org
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a potent intercellular signaling
molecule involved in multiple homeostatic functions. PACAP/PAC1 receptor signaling …
molecule involved in multiple homeostatic functions. PACAP/PAC1 receptor signaling …
Characterization of the pharmacology, signal transduction and internalization of the fluorescent PACAP ligand, fluor-PACAP, on NIH/3T3 cells expressing PAC1
PM Germano, J Stalter, SV Le, M Wu, DJ Yamaguchi… - Peptides, 2001 - Elsevier
Fluor-PACAP, a fluorescent derivative of PACAP-27, has been confirmed to share a high
affinity for PAC1 receptors transfected into NIH/3T3 cells and to have comparable …
affinity for PAC1 receptors transfected into NIH/3T3 cells and to have comparable …
Developmental regulation of pituitary adenylate cyclase-activating polypeptide and PAC1 receptor mRNA expression in the rat central nervous system
DM Jaworski, MD Proctor - Developmental Brain Research, 2000 - Elsevier
As the brain develops, a homogeneous population of mitotically active progenitors
generates the molecularly heterogeneous post-mitotic cells of the mature brain. The balance …
generates the molecularly heterogeneous post-mitotic cells of the mature brain. The balance …
PACAP type I receptor activation promotes cerebellar neuron survival through the cAMP/PKA signaling pathway
PK Campard, C Crochemore, F Rene… - DNA and cell …, 1997 - liebertpub.com
The molecular nature, transduction pathways, and neurotrophic functions of pituitary
adenylate cyclase activating peptide (PACAP) receptors were studied in primary culture of …
adenylate cyclase activating peptide (PACAP) receptors were studied in primary culture of …
PAC1, VPAC1, and VPAC2 Receptor Expression in Rat and Human Trigeminal Ganglia: Characterization of PACAP-Responsive Receptor Antibodies
Pituitary adenylate cyclase-activating peptide (PACAP) is a neuropeptide expressed in the
trigeminal ganglia (TG). The TG conducts nociceptive signals in the head and may play roles …
trigeminal ganglia (TG). The TG conducts nociceptive signals in the head and may play roles …
PACAP signaling in stress: insights from the chromaffin cell
Pituitary adenylate cyclase-activating polypeptide (PACAP) was first identified in
hypothalamus, based on its ability to elevate cyclic AMP in the anterior pituitary. PACAP has …
hypothalamus, based on its ability to elevate cyclic AMP in the anterior pituitary. PACAP has …
Specific interaction between the hop1 intracellular loop 3 domain of the human PAC1 receptor and ARF
E Ronaldson, DN Robertson, MS Johnson… - Regulatory peptides, 2002 - Elsevier
The PAC1, VPAC1 and VPAC2 receptors are members of the secretin (Group II) family of G
protein-coupled receptors. All members of this family activate adenylate cyclase and several …
protein-coupled receptors. All members of this family activate adenylate cyclase and several …