Virus-like particles: Revolutionary platforms for developing vaccines against emerging infectious diseases

H Tariq, S Batool, S Asif, M Ali, BH Abbasi - Frontiers in microbiology, 2022 - frontiersin.org
Virus-like particles (VLPs) are nanostructures that possess diverse applications in
therapeutics, immunization, and diagnostics. With the recent advancements in biomedical …

Major findings and recent advances in virus–like particle (VLP)-based vaccines

MO Mohsen, L Zha, G Cabral-Miranda… - Seminars in …, 2017 - Elsevier
Virus-like particles (VLPs) have made giant strides in the field of vaccinology over the last
three decades. VLPs constitute versatile tools in vaccine development due to their …

The application of virus-like particles as vaccines and biological vehicles

D Yan, YQ Wei, HC Guo, SQ Sun - Applied microbiology and …, 2015 - Springer
Virus-like particles (VLPs) can be spontaneously self-assembled by viral structural proteins
under appropriate conditions in vitro while excluding the genetic material and potential …

[PDF][PDF] Advances and challenges in enveloped virus-like particle (VLP)-based vaccines

S Dai, H Wang, F Deng - Journal of …, 2018 - immunologyresearchjournal.com
Virus-like particles (VLPs) are highly organized particles that self-assemble from viral
structural proteins. Like parental viruses, VLPs can be either non-enveloped or enveloped …

Vaccination, immune and gene therapy based on virus-like particles against viral infections and cancer

T Ramqvist, K Andreasson… - Expert opinion on …, 2007 - Taylor & Francis
Virus-like particles (VLPs) are self-assembling, non-replicating particles lacking the viral
genome that are formed by one or several viral structural proteins. VLPs can be purified after …

Virus-like particles: the new frontier of vaccines for animal viral infections

E Crisci, J Bárcena, M Montoya - Veterinary immunology and …, 2012 - Elsevier
Vaccination continues to be the main approach to protect animals from infectious diseases.
Until recently, all licensed vaccines were developed using conventional technologies …

Synthetic biology for bioengineering virus‐like particle vaccines

HK Charlton Hume, J Vidigal… - Biotechnology and …, 2019 - Wiley Online Library
Vaccination is the most effective method of disease prevention and control. Many viruses
and bacteria that once caused catastrophic pandemics (eg, smallpox, poliomyelitis …

Virus‑like particles as a vaccine delivery system: Myths and facts

P Roy, R Noad - Human vaccines, 2008 - Taylor & Francis
Vaccines against viral disease have traditionally relied on attenuated virus strains or
inactivation of infectious virus. Subunit vaccines based on viral proteins expressed in …

Virus-like particles: potential veterinary vaccine immunogens

F Liu, S Ge, L Li, X Wu, Z Liu, Z Wang - Research in veterinary science, 2012 - Elsevier
Virus-like particle (VLP) composed of outer shell but no genome of virus mimics the natural
configuration of authentic virion and has no characteristics of self-replication. A close …

Bioengineering virus‐like particles as vaccines

LHL Lua, NK Connors, F Sainsbury… - Biotechnology and …, 2014 - Wiley Online Library
Virus‐like particle (VLP) technology seeks to harness the optimally tuned immunostimulatory
properties of natural viruses while omitting the infectious trait. VLPs that assemble from a …