In recent years, the development of novel recombinant virus‐like particles (VLPs) has been generating new perspectives for the prevention of untreated and arising infectious diseases …
B Schwarz, T Douglas - Wiley Interdisciplinary Reviews …, 2015 - Wiley Online Library
As ordered nanoscale architectures, viruses and virus‐like particles (VLP s) remain unsurpassed by synthetic strategies to produce uniform and symmetric nanoparticles …
Highlights•Safety and potency of simian adenovirus vectors is now well established, most recently in infants.•Viral vectored vaccines are effective against malaria and Ebola in field …
Virus-like particles are supra-molecular assemblages, usually icosahedral or rod-like structures. They incorporate key immunologic features of viruses which include repetitive …
Cancers have killed millions of people in human history and are still posing a serious health problem worldwide. Therefore, there is an urgent need for developing preventive and …
Highlights•VLP have been engineered to improve their utility as vaccine platforms.•Targeted engineering of VLPs has enhanced immunogenicity, stability, and versatility.•Predictive …
Mosquito borne viral diseases are an emerging threat as evident from the recent outbreak of Zika virus (ZIKV) as well as repeated outbreaks of Chikungunya (CHIKV), Yellow fever (YFV) …
KD Brune, M Howarth - Frontiers in immunology, 2018 - frontiersin.org
Vaccines based on virus-like particles (VLPs) can induce potent B cell responses. Some non- chimeric VLP-based vaccines are highly successful licensed products (eg, hepatitis B …
C López-Macías - Human vaccines & immunotherapeutics, 2012 - Taylor & Francis
The influenza pandemic of 2009 demonstrated the inability of the established global capacity for egg-based vaccine production technology to provide sufficient vaccine for the …