THE oncoprotein c-Jun is thought to be a mediator of ras transformation as both its synthesis
and activity as a transcription factor are stimulated by ras expression1, 2. But c-Jun co …

The JUN protooncogene encodes a protein that is functionally and biochemically identical to
the transcription factor AP-1 (activator protein 1). To understand the structure and regulation …

We have isolated chicken genomic and cDNA clones representing the jun oncogene of
avian sarcoma virus 17 (ASV17). The genomic clone lacks intron sequences within its …

The activity of c-Jun is regulated by phosphorylation. Various stimuli including transforming
oncogenes and UV light, induce phosphorylation of serines 63 and 73 in the amino-terminal …

Transcription factor c-Jun appears to be a nuclear target of the Ras-induced signal
transduction pathway. In fact, some experiments show that transforming forms of the Ras …

The transcriptional activity of c-Jun is augmented through phosphorylation at two sites by a c-
Jun amino-terminal kinase (JNK). All cells express two distinct JNK activities, 46 and 55 kD …

In this study we report the identification of a novel transcription factor, termed Nuclear Factor‐
jun (NF‐jun). This factor contributes to inducible transcription of the c‐jun gene in human …

Abstract nit-4, a pathway-specific regulatory gene in the nitrogen circuit of Neurospora
crassa, is required for the expression of nit-3 and nit-6, the structural genes which encode …

The ability of the nuclear oncoprotein Jun to activate transcription is controlled both by level
of DNA binding and by the activity of its transactivation domain. Control of DNA binding is …

The yeast transcriptional regulator protein GCN4 harbors the bZIP DNA binding motif, which
is common to a family of DNA-binding proteins in eukaryotic organisms from yeast to man …