Transformation by Raf and other oncogenes renders cells differentially sensitive to growth inhibition by a dominant negative c-jun mutant.
UR Rapp, J Troppmair, T Beck, MJ Birrer - Oncogene, 1994 - europepmc.org
In NIH3T3 cells expressing active Raf-1 protein serine/threonine kinase (PSK) c-jun
expression is constitutive while c-fos expression is attenuated. This alteration prompted us to …
expression is constitutive while c-fos expression is attenuated. This alteration prompted us to …
The Neurospora aab-1 gene encodes a CCAAT binding protein homologous to yeast HAP5
H Chen, JW Crabb, JA Kinsey - Genetics, 1998 - academic.oup.com
The expression of the am (glutamate dehydrogenase) gene is dependent upon two
upstream activating sequences, designated URSamα and URSamβ. A heteromeric nuclear …
upstream activating sequences, designated URSamα and URSamβ. A heteromeric nuclear …
Molecular Analysis of GCN3, a Translational Activator of GCN4: Evidence for Posttranslational Control of GCN3 Regulatory Function
EM Hannig, AG Hinnebusch - Molecular and cellular biology, 1988 - Taylor & Francis
GCN4 encodes a transcriptional activator of amino acid biosynthetic genes in
Saccharomyces cerevisiae. The GCN3 product is a positive regulator required for increased …
Saccharomyces cerevisiae. The GCN3 product is a positive regulator required for increased …
The CCR4 gene from Saccharomyces cerevisiae is required for both nonfermentative and spt-mediated gene expression.
CL Denis, T Malvar - Genetics, 1990 - academic.oup.com
Mutations in the yeast CCR4 gene inhibit expression of the glucose-repressible alcohol
dehydrogenase (ADH2), as well as other nonfermentative genes, and suppress increased …
dehydrogenase (ADH2), as well as other nonfermentative genes, and suppress increased …
[HTML][HTML] Different members of the jun proto-oncogene family exhibit distinct patterns of expression in response to type beta transforming growth factor.
L Li, JS Hu, EN Olson - Journal of Biological Chemistry, 1990 - Elsevier
Type beta transforming growth factor (TGF-beta) is a multifunctional regulator of cell growth
and differentiation. In the BC3H1 muscle cell line, TGF-beta blocks the onset of …
and differentiation. In the BC3H1 muscle cell line, TGF-beta blocks the onset of …
Transcriptional regulation of the junB promoter: analysis of STAT-mediated signal transduction.
P Coffer, C Lutticken, A Van Puijenbroek… - Oncogene, 1995 - europepmc.org
The product of the junB gene is a member of the AP-1 family of transcription factors that
activate transcription by binding to TPA-responsive elements (TREs) within the promoters of …
activate transcription by binding to TPA-responsive elements (TREs) within the promoters of …
The cell-type-specific activator region of c-Jun juxtaposes constitutive and negatively regulated domains.
VR Baichwal, A Park, R Tjian - Genes & development, 1992 - genesdev.cshlp.org
Dissection of the cell-type-specific activation region in c-Jun reveals two functionally
separable regulatory subdomains. One subdomain (a1) functions as a transcriptional …
separable regulatory subdomains. One subdomain (a1) functions as a transcriptional …
[PDF][PDF] Molecular mechanisms of transcriptional regulation in yeast
K Struhl - Annual review of biochemistry, 1989 - struhl.hms.harvard.edu
1052 STRUHL various steps along the pathway. Nevertheless, a major point of gene control
occurs at the first step, namely the initiation of messenger RNA synthesis. Over the past …
occurs at the first step, namely the initiation of messenger RNA synthesis. Over the past …
Efficient transformation of chicken embryo fibroblasts by c-Jun requires structural modification in coding and noncoding sequences.
TJ Bos, FS Monteclaro, F Mitsunobu… - Genes & …, 1990 - genesdev.cshlp.org
To assess the transforming capability of the c-Jun protein, we introduced the chicken c-jun
proto-oncogene into a replication competent avian retroviral expression vector (RCAS). Viral …
proto-oncogene into a replication competent avian retroviral expression vector (RCAS). Viral …
SPARC and thrombospondin genes are repressed by the c‐jun oncogene in rat embryo fibroblasts.
A Mettouchi, F Cabon, N Montreau, P Vernier… - The EMBO …, 1994 - embopress.org
The sequence‐specific transcription factor c‐Jun displays oncogenic potential in
mammalian cells either in cooperation with activated Ras in primary embryonic fibroblasts or …
mammalian cells either in cooperation with activated Ras in primary embryonic fibroblasts or …