The jun oncoprotein, which causes sarcomas in chickens, and the DNA-binding domain of
yeast GCN4, which coordinately regulates the expression of amino acid biosynthetic genes …

The product of the recently described oncogene jun shows significant amino acid sequence
homology with the GCN4 yeast transcriptional activator protein. The similarity is restricted to …

Transcriptional activation of RNA polymerase II in eukaryotic organisms ranging from yeasts
to mammals has many common features such as enhancer elements, TATA elements, and …

Jun is a transcription factor that can also induce oncogenic transformation. Its tional
equivalence. A chimeric GCN4 DNA-binding domain is conserved from yeast to man and …

In an extensive screen of a cDNA library prepared from serum‐stimulated mouse NIH 3T3
cells, we identified three distinct jun‐related clones. Two of them were carrying c‐jun and …

Proto-oncogenes encode proteins with three main sites of action: the cell-surface
membrane, the cytoplasm and the nucleus1, 2. Although the exact biochemical function of …

The Jun and Fos oncoproteins belong to the AP-1 family of transcriptional activators and are
believed to induce cellular transformation by inappropriately activating genes involved in …

Oncogene research has led to the isolation of specific reagents that have allowed important
insights in several disciplines. Recently, studies on oncogenes encoding nuclear proteins …

Transcription factor AP-1 is constituted by the products of the various fos and jun genes. AP-
1 activity is modulated by second messengers and appears to involve post-translational …

By means of low-stringency cross-species hybridization to Southern DNA blots, human c-jun
sequences were used to identify a unique Drosophila melanogaster locus (Djun). The …