Transcriptional Autoregulation and Inhibition of mRNA Translation of Amino Acid Regulator Gene cpcA of Filamentous FungusAspergillus nidulans

B Hoffmann, O Valerius, M Andermann… - Molecular biology of …, 2001 - Am Soc Cell Biol
The CPCA protein of the filamentous fungus Aspergillus nidulans is a member of the c-Jun-
like transcriptional activator family. It acts as central transcription factor of the cross-pathway …

cpc-3, the Neurospora crassa homologue of yeast GCN2, encodes a polypeptide with juxtaposed eIF2α kinase and histidyl-tRNA synthetase-related domains required …

E Sattlegger, AG Hinnebusch, IB Barthelmess - Journal of Biological …, 1998 - ASBMB
Based on characteristic amino acid sequences of kinases that phosphorylate the α subunit
of eukaryotic translation initiation factor 2 (eIF2α kinases), degenerate oligonucleotide …

The Aspergillus nigerGCN4 homologue, cpcA, is transcriptionally regulated and encodes an unusual leucine zipper

C Wanke, S Eckert, G Albrecht… - Molecular …, 1997 - Wiley Online Library
The general control transcriptional regulator gene cpcA of Aspergillus niger was cloned by
complementation of a Saccharomyces cerevisiaeΔgcn4 mutant strain. The encoded protein …

The Aspergillus fumigatus transcriptional activator CpcA contributes significantly to the virulence of this fungal pathogen

S Krappmann, EM Bignell, U Reichard… - Molecular …, 2004 - Wiley Online Library
We have cloned and characterized the Aspergillus fumigatus cpcA gene encoding the
transcriptional activator of the cross‐pathway control system of amino acid biosynthesis …

The cross-pathway control gene of Neurospora crassa, cpc-1, encodes a protein similar to GCN4 of yeast and the DNA-binding domain of the oncogene v-jun …

JL Paluh, MJ Orbach, TL Legerton… - Proceedings of the …, 1988 - National Acad Sciences
Expression of the gene cpc-1 is required for cross-pathway-mediated regulation of amino
acid-biosynthetic genes in Neurospora crassa. We have cloned cpc-1 and present an …

Translational regulation in response to changes in amino acid availability in Neurospora crassa

Z Luo, M Freitag, MS Sachs - Molecular and cellular biology, 1995 - Am Soc Microbiol
We examined the regulation of Neurospora crassa arg-2 and cpc-1 in response to amino
acid availability. arg-2 encodes the small subunit of arginine-specific carbamoyl phosphate …

cpc-1, the General Regulatory Gene for Genes of Amino Acid Biosynthesis in Neurospora crassa, Is Differentially Expressed during the Asexual Life Cycle

DJ Ebbole, JL Paluh, M Plamann… - … and cellular biology, 1991 - Taylor & Francis
CPC1, the principal regulatory protein required for cross-pathway control of amino acid
biosynthetic genes in Neurospora crassa, contains a domain similar to the DNA-binding …

Translation initiation from conserved non-AUG codons provides additional layers of regulation and coding capacity

IP Ivanov, J Wei, SZ Caster, KM Smith, AM Michel… - MBio, 2017 - Am Soc Microbiol
Neurospora crassa cpc-1 and Saccharomyces cerevisiae GCN4 are homologs specifying
transcription activators that drive the transcriptional response to amino acid limitation. The …

Transcriptional-translational regulatory circuit in Saccharomyces cerevisiae which involves the GCN4 transcriptional activator and the GCN2 protein kinase

I Roussou, G Thireos, BM Hauge - Molecular and cellular biology, 1988 - Am Soc Microbiol
GCN4 protein mediates the transcriptional activation of amino acid biosynthetic genes in
Saccharomyces cerevisiae by specifically binding to DNA sequences in their 5′-regulatory …

Characterization of Neurospora CPC1, a bZIP DNA-Binding Protein That Does Not Require Aligned Heptad Leucines for Dimerization

JL Paluh, C Yanofsky - Molecular and cellular biology, 1991 - Taylor & Francis
CPC1 is the transcriptional activator of amino acid biosynthetic genes of Neurospora crassa.
CPC1 function in vivo was abolished upon deletion of segments of cpc-1 corresponding to …