[HTML][HTML] An integrative analysis of meningioma tumors reveals the determinant genes and pathways of malignant transformation

JC Iglesias Gómez, A Mosquera Orgueira - Frontiers in oncology, 2014 - frontiersin.org
Meningiomas are frequent central nervous system neoplasms, which despite their
predominant benignity, show sporadically malignant behavior. Type 2 neurofibromatosis …

Genomic and transcriptome analysis revealing an oncogenic functional module in meningiomas

X Chang, L Shi, F Gao, J Russin, L Zeng, S He… - Neurosurgical …, 2013 - thejns.org
Object Meningiomas are among the most common primary adult brain tumors. Although
typically benign, roughly 2%–5% display malignant pathological features. The key molecular …

[HTML][HTML] The multiomic landscape of meningiomas: a review and update

JZ Wang, F Nassiri, AP Landry, V Patil, J Liu… - Journal of Neuro …, 2023 - Springer
Purpose Meningiomas are the most common primary brain tumor in adults. Traditionally they
have been understudied compared to other central nervous system (CNS) tumors. However …

[HTML][HTML] Molecular signatures define two main classes of meningiomas

LH Carvalho, I Smirnov, GS Baia, Z Modrusan… - Molecular cancer, 2007 - Springer
Background Meningiomas are common brain tumors that are classified into three World
Health Organization grades (benign, atypical and malignant) and are molecularly ill-defined …

Holistic and network analysis of meningioma pathogenesis and malignancy

Y Tao, Q Wei, Z Xu, R Bai, Y Li, C Luo, Y Dong… - Biofactors, 2006 - Wiley Online Library
Meningiomas, which originate from arachnoid cells and constitute the largest subgroup of all
intracranial tumors, are generally benign, yet have the capacity to progress into a higher …

Molecular alterations in meningiomas: Literature review

BJA Pereira, SM Oba-Shinjo, AN de Almeida… - Clinical neurology and …, 2019 - Elsevier
Meningiomas, tumors that originate from meningothelial cells, account for approximately
30% of all new diagnoses of central nervous system neoplasms. According to the 2016 …

Genomic landscape of meningiomas

Y Lee, J Liu, S Patel, T Cloughesy, A Lai… - Brain …, 2010 - Wiley Online Library
Meningiomas are one of the most common adult brain tumors. For most patients, surgical
excision is curative. However, up to 20% recur. Currently, the molecular determinants …

Genome-wide association analysis identifies a meningioma risk locus at 11p15. 5

EB Claus, AJ Cornish, P Broderick… - Neuro …, 2018 - academic.oup.com
Background Meningiomas are adult brain tumors originating in the meningeal coverings of
the brain and spinal cord, with significant heritable basis. Genome-wide association studies …

[HTML][HTML] Exome sequencing on malignant meningiomas identified mutations in neurofibromatosis type 2 (NF2) and meningioma 1 (MN1) genes

X Zhang, H Jia, Y Lu, C Dong, J Hou, Z Wang… - Discovery …, 2014 - ncbi.nlm.nih.gov
Background Meningiomas are tumors originating from the membranous layers surrounding
the central nervous system, and are generally regarded as “benign” tumors of the brain …

[HTML][HTML] Genomic biomarkers of meningioma: a focused review

JA Pawloski, HA Fadel, YW Huang, IY Lee - International Journal of …, 2021 - mdpi.com
Meningiomas represent a phenotypically and genetically diverse group of tumors which
often behave in ways that are not simply explained by their pathologic grade. The genetic …