Neutralizing monoclonal antibodies against the Nogo-66 receptor (NgR) and uses thereof

M Mezler, A Moeller, R Mueller, BK Mueller… - US Patent …, 2018 - Google Patents
The subject invention relates to isolated proteins, particu larly monoclonal antibodies, which
bind to the Nogo-66 receptor. Specifically, these antibodies have the ability to inhibit the …

Methods of treating conditions involving neuronal degeneration

KF So, W Wu - 2009 - hub.hku.hk
The HKU Scho吋 Hub - TheUmwsg of Hong Kong 香 港大晕 晕衍摩 Page 1 The HKU Scho吋
Hub - TheUmwsg of Hong Kong 香 港大晕 晕衍摩 - - 丁 一人 ■ ( 翌季 - 爱 ** _ ■ ! - - - 量 …

Methods of Treating Conditions Involving Neuronal Degeneration

LD HS, SD WY, KF So, W Wu - 2009 - hub.hku.hk
Title Methods of Treating Conditions Involving Neuronal Degeneration Inventor(s) Lee
Daniel HS; Sah Dinah WY; So, KF; Wu, W Ci Page 1 Title Methods of Treating Conditions …

Nogo receptor homologs that decrease inhibition of axonal elongation

S Strittmatter, RL Cate, DWY Sah - US Patent 7,456,255, 2008 - Google Patents
2010-03-19 Assigned to NATIONAL INSTITUTES OF HEALTH (NIH), US DEPT. OF HEALTH
AND HUMAN SERVICES (DHHS), US GOVERNMENT reassignment NATIONAL …

Nogo-A Polypeptide Fragments, Variant Nogo Receptor-1 Polypeptides, and Uses Thereof

SM Strittmatter - US Patent App. 11/576,413, 2009 - Google Patents
Nogo, MAG, and OMgp are myelin-derived proteins that bind to a neuronal Nogo-66
Receptor (NgR) to limit axonal regeneration after CNS injury. Nogo-A protein may play the …

Use of lingo-4 antagonists in the treatment of conditions involving demyelination

S Mi, RB Pepinsky, J McCoy - US Patent App. 14/978,289, 2016 - Google Patents
0001 1. Field of the Invention 0002 This invention relates to neurobiology, neurology and
pharmacology. More particularly, it relates to methods for treating demylelination …

Nogo receptor homologues and their use

C Barske, S Frentzel, K Kaupmann… - US Patent App. 11 …, 2008 - Google Patents
This invention relates to gene polypeptides and polynucle otides that encode proteins of the
Nogo-66 receptor (NgR) family and are therefore called NgRhomologue 2 (NgRH2). The …

Antibody (11C7) anti nogo a and its pharmaceutical use

C Barske, AK Mir, T Oertle, L Schnell… - US Patent …, 2010 - Google Patents
This invention relates to molecules, such as for example monoclonal antibodies or Fab
fragments thereof, which are capable of binding to the human NogoA polypeptide or human …

Methods for modulating the axonal outgrowth of central nervous system neurons

LI Benowitz - US Patent 6,551,612, 2003 - Google Patents
US6551612B2 - Methods for modulating the axonal outgrowth of central nervous system
neurons - Google Patents US6551612B2 - Methods for modulating the axonal outgrowth of …

[引用][C] Promoters of neural regeneration

H Song, M Poo, G Ming, M Tessier-Lavigne, Z He