IRF-1 acts as a positive regulator in the transcription of grass carp (Ctenopharyngodon idella) IFN gene
Q Lai, G Lin, M Ma, S Huang, W Li, D Li, M Gu… - Fish & shellfish …, 2013 - Elsevier
Interferon regulatory factors (IRFs) are well-known to be crucial for modulating the innate
immune responses to viral infections. In the present study, the IRF-1 gene of grass carp …
immune responses to viral infections. In the present study, the IRF-1 gene of grass carp …
Expression profile of carp IFN correlate with the up-regulation of interferon regulatory factor-1 (IRF-1) in vivo and in vitro: the pivotal molecules in antiviral defense
S Shan, C Qi, Y Zhu, H Li, L An, G Yang - Fish & shellfish immunology, 2016 - Elsevier
Interferon regulatory factors (IRFs) are a family of transcription factors that mediate the
transcriptional regulation of interferon (IFN) genes and IFN-inducible genes. In this study …
transcriptional regulation of interferon (IFN) genes and IFN-inducible genes. In this study …
Ctenopharyngodon idella IRF2 plays an antagonistic role to IRF1 in transcriptional regulation of IFN and ISG genes
M Gu, G Lin, Q Lai, B Zhong, Y Liu, Y Mi, H Chen… - Developmental & …, 2015 - Elsevier
Abstract Interferon Regulatory Factors (IRFs) make up a family of transcription factors
involved in transcriptional regulation of type I IFN and IFN-stimulated genes (ISG) in cells. In …
involved in transcriptional regulation of type I IFN and IFN-stimulated genes (ISG) in cells. In …
Molecular characterization and transcription regulation analysis of type I IFN gene in grass carp (Ctenopharyngodon idella)
D Li, W Tan, M Ma, X Yu, Q Lai, Z Wu, G Lin, C Hu - Gene, 2012 - Elsevier
Type I interferons and interferon regulatory factor 7 (IRF7), which are crucial for innate
immunity against viral infection, have been identified in many teleost fishes in recent years …
immunity against viral infection, have been identified in many teleost fishes in recent years …
Molecular characterization and immune functional analysis of IRF2 in common carp (Cyprinus carpio L.): different regulatory role in the IFN and NF-κB signalling …
H Li, X Chen, Y Zhu, R Liu, L Zheng, S Shan… - BMC Veterinary …, 2021 - Springer
Background Interferon regulatory factor 2 (IRF2) is an important transcription factor, which
can regulate the IFN response and plays a role in antiviral innate immunity in teleost …
can regulate the IFN response and plays a role in antiviral innate immunity in teleost …
Fish IRF3 up-regulates the transcriptional level of IRF1, IRF2, IRF3 and IRF7 in CIK cells
X Xu, Q Lai, M Gu, D Liu, Q Hou, X Liu, Y Mi… - Fish & Shellfish …, 2015 - Elsevier
Abstract Interferon Regulatory Factors (IRFs) belong to a family of transcription factor
involved in transcriptional regulation of type I IFN and IFN-stimulated genes (ISG) in cells. In …
involved in transcriptional regulation of type I IFN and IFN-stimulated genes (ISG) in cells. In …
Molecular cloning and expression of IRF1 in large yellow croaker, Pseudosciaena crocea
CL Yao, P Kong, XN Huang, ZY Wang - Fish & Shellfish Immunology, 2010 - Elsevier
The interferon regulatory factor (IRF) family is known to be crucial in mediating the host
defense against pathogen infection by binding to characteristic elements in promoters within …
defense against pathogen infection by binding to characteristic elements in promoters within …
Identification of an IRF10 gene in common carp (Cyprinus carpio L.) and analysis of its function in the antiviral and antibacterial immune response
Y Zhu, S Shan, H Zhao, R Liu, H Wang, X Chen… - BMC veterinary …, 2020 - Springer
Background Interferon (IFN) regulatory factors (IRFs), as transcriptional regulatory factors,
play important roles in regulating the expression of type I IFN and IFN-stimulated genes …
play important roles in regulating the expression of type I IFN and IFN-stimulated genes …
A conserved interferon regulation factor 1 (IRF-1) from Pacific oyster Crassostrea gigas functioned as an activator of IFN pathway
M Lu, C Yang, M Li, Q Yi, G Lu, Y Wu, C Qu… - Fish & shellfish …, 2018 - Elsevier
Interferon regulatory factors (IRFs), a family of transcription factors with a novel helix-turn-
helix DNA-binding motif, play important roles in regulating the expression of interferons …
helix DNA-binding motif, play important roles in regulating the expression of interferons …
Identification and functional characterization of miiuy croaker IRF3 as an inducible protein involved regulation of IFN response
C Shu, Q Chu, D Bi, Y Wang, T Xu - Fish & Shellfish Immunology, 2016 - Elsevier
IFN regulatory factor (IRF) 3 as an important member of IRF family, is required for the host
antiviral response. In mammals, IRF3 is known to be a critical player in regulating the …
antiviral response. In mammals, IRF3 is known to be a critical player in regulating the …