Characterizing whole proteins by top-down proteomics avoids a step of inference
encountered in the dominant bottom-up methodology when peptides are assembled …

The protein composition of animal venoms is usually determined by peptide-centric
proteomics approaches (bottom-up proteomics). However, this technique cannot, in most …

Snake venom proteomes are complex mixtures of a large number of distinct proteins. In a
sense, the field of snake venom proteomics has been under investigation since the very …

Snake venoms consist of highly biologically active proteins and peptides that are
responsible for the lethal physiological effects of snakebite envenomation. In order to guide …

Snake venoms contain complex mixtures of proteins vital for the survival of venomous
snakes. Aligned with their diverse pharmacological activities, the protein compositions of …

The venom produced by snakes contains complex mixtures of pharmacologically active
proteins and peptides which play a crucial role in the pathophysiology of snakebite …

Snake venom is a complex mixture of proteins and peptides, and a number of studies have
described the biological properties of several venomous proteins. Nevertheless, a complete …

Introduction: Venoms are integrated phenotypes used by a wide range of organisms for
predatory and defensive purposes. The study of venoms is of great interest in diverse fields …

Snake venoms are primarily composed of proteins and peptides, and these toxins have
developed high selectivity to their biological targets. This makes venoms interesting for …

A large-scale proteomic approach was devised to advance the understanding of venom
composition. Bothrops jararaca venom was fractionated by OFFGEL followed by …