Direct oral anticoagulants vs vitamin K antagonists in patients with antiphospholipid syndromes: meta-analysis of randomized trials

CD Khairani, A Bejjani, G Piazza, D Jimenez… - Journal of the American …, 2023 - jacc.org
Background The efficacy and safety of direct oral anticoagulants (DOACs) for patients with
thrombotic antiphospholipid syndrome remain controversial. Objectives The authors …

Direct oral anticoagulants in antiphospholipid syndrome: meta-analysis of randomized controlled trials

V Dufrost, D Wahl, S Zuily - Autoimmunity reviews, 2021 - Elsevier
Background The gold standard for secondary thromboprophylaxis in APS is long term
anticoagulation with vitamin K antagonists (VKAs). Because of their widespread use and …

Increased risk of thrombosis in antiphospholipid syndrome patients treated with direct oral anticoagulants. Results from an international patient-level data meta …

V Dufrost, J Risse, T Reshetnyak, M Satybaldyeva… - Autoimmunity …, 2018 - Elsevier
Abstract Background Direct oral anticoagulants (DOACs) are widely used for secondary
prevention of venous thromboembolism (VTE) but their clinical efficacy and safety are not …

Use of direct oral anticoagulants in patients with antiphospholipid syndrome: a systematic review and comparison of the international guidelines

D Pastori, D Menichelli, V Cammisotto… - Frontiers in …, 2021 - frontiersin.org
Antiphospholipid antibody syndrome (APS) requires long-term anticoagulation to prevent
recurrent thrombosis. Direct oral anticoagulants (DOACs) have been increasingly used in …

Direct oral anticoagulants use in antiphospholipid syndrome: are these drugs an effective and safe alternative to warfarin? A systematic review of the literature

V Dufrost, J Risse, S Zuily, D Wahl - Current rheumatology reports, 2016 - Springer
Background The cornerstone of thrombotic antiphospholipid syndrome (APS) patients'
management is to prevent recurrent thrombosis by long-term anticoagulation. Purpose of …

[HTML][HTML] Use of direct oral anticoagulants in antiphospholipid syndrome

H Cohen, M Efthymiou, DA Isenberg - Journal of Thrombosis and …, 2018 - Elsevier
The direct oral anticoagulants (DOACs) are therapeutic alternatives to warfarin and other
vitamin K antagonists (VKAs), and constitute the standard of care for many indications. VKAs …

Rivaroxaban versus vitamin K antagonist in antiphospholipid syndrome: a randomized noninferiority trial

J Ordi-Ros, L Sáez-Comet… - Annals of internal …, 2019 - acpjournals.org
Background: The potential role of new oral anticoagulants in antiphospholipid antibody
syndrome (APS) remains uncertain. Objective: To determine whether rivaroxaban is …

Apixaban compared with warfarin to prevent thrombosis in thrombotic antiphospholipid syndrome: a randomized trial

SC Woller, SM Stevens, D Kaplan, TF Wang… - Blood …, 2022 - ashpublications.org
Thrombotic antiphospholipid syndrome (TAPS) is characterized by venous, arterial, or
microvascular thrombosis. Patients with TAPS merit indefinite anticoagulation, and warfarin …

Trial of rivaroxaban in antiPhospholipid syndrome (TRAPS): two‐year outcomes after the study closure

V Pengo, A Hoxha, L Andreoli, A Tincani… - … of thrombosis and …, 2021 - Wiley Online Library
Abstract Background Trial of Rivaroxaban in AntiPhospholipid Syndrome was a prospective
randomized, open‐label, noninferiority study conducted in 14 centers in Italy. Rivaroxaban …

Rivaroxaban vs warfarin in high-risk patients with antiphospholipid syndrome

V Pengo, G Denas, G Zoppellaro… - Blood, The Journal …, 2018 - ashpublications.org
Rivaroxaban is an effective and safe alternative to warfarin in patients with atrial fibrillation
and venous thromboembolism. We tested the efficacy and safety of rivaroxaban compared …