Exploring snake venom proteomes: multifaceted analyses for complex toxin mixtures

JW Fox, SMT Serrano - Proteomics, 2008 - Wiley Online Library
Snake venom proteomes are complex mixtures of a large number of distinct proteins. In a
sense, the field of snake venom proteomics has been under investigation since the very …

Comparison of indirect and direct approaches using ion-trap and Fourier transform ion cyclotron resonance mass spectrometry for exploring viperid venom proteomes

JW Fox, L Ma, K Nelson, NE Sherman, SMT Serrano - Toxicon, 2006 - Elsevier
In a sense, the field of snake venom proteomics has been under investigation since the very
earliest biochemical studies where it was soon recognized that venoms are comprised of …

Investigating toxin diversity and abundance in snake venom proteomes

T Tasoulis, TL Pukala, GK Isbister - Frontiers in Pharmacology, 2022 - frontiersin.org
Understanding snake venom proteomes is becoming increasingly important to understand
snake venom biology, evolution and especially clinical effects of venoms and approaches to …

Deadly proteomes: a practical guide to proteotranscriptomics of animal venoms

AA Walker, SD Robinson, BF Hamilton… - …, 2020 - Wiley Online Library
Animal venoms are renowned for their toxicity, biochemical complexity, and as a source of
compounds with potential applications in medicine, agriculture, and industry. Polypeptides …

Snake venomics. Strategy and applications

JJ Calvete, P Juárez, L Sanz - Journal of mass spectrometry, 2007 - Wiley Online Library
Snake bites can be deadly, but the venoms also contain components of medical and
biotechnological value. The proteomic characterization of snake venom proteomes, snake …

Snake venomics–from low-resolution toxin-pattern recognition to toxin-resolved venom proteomes with absolute quantification

JJ Calvete - Expert Review of Proteomics, 2018 - Taylor & Francis
Introduction: Venoms are integrated phenotypes used by a wide range of organisms for
predatory and defensive purposes. The study of venoms is of great interest in diverse fields …

Snake venomics: fundamentals, recent updates, and a look to the next decade

CH Tan - Toxins, 2022 - mdpi.com
Venomic research, powered by techniques adapted from proteomics, transcriptomics, and
genomics, seeks to unravel the diversity and complexity of venom through which knowledge …

An in-depth snake venom proteopeptidome characterization: Benchmarking Bothrops jararaca

CA Nicolau, PC Carvalho… - Journal of …, 2017 - Elsevier
A large-scale proteomic approach was devised to advance the understanding of venom
composition. Bothrops jararaca venom was fractionated by OFFGEL followed by …

Proteome analysis of snake venom toxins: pharmacological insights

D Georgieva, RK Arni, C Betzel - Expert review of proteomics, 2008 - Taylor & Francis
Snake venoms are an extremely rich source of pharmacologically active proteins with a
considerable clinical and medical potential. To date, this potential has not been fully …

Venom gland transcriptomics for identifying, cataloging, and characterizing venom proteins in snakes

RK Brahma, RJR McCleary, RM Kini, R Doley - Toxicon, 2015 - Elsevier
Snake venoms are cocktails of protein toxins that play important roles in capture and
digestion of prey. Significant qualitative and quantitative variation in snake venom …