Bioinspired Multiscale Biomaterials for Cell-Based Medicine

S Zhao - 2016 - rave.ohiolink.edu
Cell-based medicine is recently attracting extensive attention as a potential therapeutic
approach for various diseases. However, major hurdles have prevented their widespread …

Bioinspired one cell culture isolates highly tumorigenic and metastatic cancer stem cells capable of multilineage differentiation

H Wang, P Agarwal, B Jiang, S Stewart, X Liu… - Advanced …, 2020 - Wiley Online Library
Cancer stem cells (CSCs) are rare cancer cells that are postulated to be responsible for
cancer relapse and metastasis. However, CSCs are difficult to isolate and poorly …

Enhanced enrichment of prostate cancer stem-like cells with miniaturized 3D culture in liquid core-hydrogel shell microcapsules

W Rao, S Zhao, J Yu, X Lu, DL Zynger, X He - Biomaterials, 2014 - Elsevier
Cancer stem-like cells (CSCs) are rare subpopulations of cancer cells that are reported to be
responsible for cancer resistance and metastasis associated with conventional cancer …

Multiscale Biomaterials for Cell and Tissue Engineering

P Agarwal - 2017 - rave.ohiolink.edu
The aim of tissue engineering is to fabricate functional tissue constructs for treating
diseases. Contemporary approach for tissue engineering is to embed cells in homogenous …

A novel core–shell microcapsule for encapsulation and 3D culture of embryonic stem cells

W Zhang, S Zhao, W Rao, J Snyder, JK Choi… - Journal of materials …, 2013 - pubs.rsc.org
In this study, we report the preparation of a novel microcapsule of∼ 100 μm with a liquid (as
compared to a solid-like alginate hydrogel) core and an alginate–chitosan–alginate (ACA) …

Microscale biomaterials with bioinspired complexity of early embryo development and in the ovary for tissue engineering and regenerative medicine

X He - ACS biomaterials science & engineering, 2017 - ACS Publications
Tissue engineering and regenerative medicine (TERM) are attracting more and more
attention for treating various diseases in modern medicine. Various biomaterials including …

Conformal Nanoencapsulation of Allogeneic T Cells Mitigates Graft-versus-Host Disease and Retains Graft-versus-Leukemia Activity

S Zhao, L Zhang, J Han, J Chu, H Wang, X Chen… - ACS …, 2016 - ACS Publications
Allogeneic transplantation of hematopoietic stem cells (HSC) in combination with T cells has
a curative potential for hematopoietic malignancies through graft-versus-leukemia (GVL) …

Tissue beads: tissue‐specific extracellular matrix microbeads to potentiate reprogrammed cell‐based therapy

JS Lee, YH Roh, YS Choi, Y Jin, EJ Jeon… - Advanced Functional …, 2019 - Wiley Online Library
Microbeads have been utilized as efficient cell culture carriers and injectable scaffolds for
cell transplantation. However, various polymers currently used to generate microbeads have …

Biomimetic cell encapsulations by microfluidics

J Wang, D Huang, Y Fang, H Ren, Y Zhao - Science China Materials, 2024 - Springer
Cell encapsulated in biomaterials for organ repair or disease treatment is indeed an
emerging field. Currently, microfluidics is being utilized to precisely control the quantity, size …

Engineered cell-originated biomimetic materials for cancer therapy

L Xiao, Y Zhang, M Zhang, J Gao - Frontiers in Bioengineering and …, 2023 - frontiersin.org
Cancer remains one of the leading causes of death worldwide and a major obstacle to
increasing human life expectancy. The traditional cancer therapies such as chemotherapy …