The challenge of more robust and reproducible methodology in screening for primary aldosteronism

RD Gordon - Journal of hypertension, 2004 - journals.lww.com
Primary aldosteronism (PAL) is gaining recognition as an important cause of hypertension,
and attention is focusing more critically on the reliability of screening tests for PAL. However …

Assay characteristics influence the aldosterone to renin ratio as a screening tool for primary aldosteronism: results of the German Conn's registry

E Fischer, S Reuschl, M Quinkler… - Hormone and …, 2013 - thieme-connect.com
Primary aldosteronism (PA) is the most frequent cause of secondary arterial hypertension.
The aldosterone to renin ratio (ARR) is the gold standard for screening, but variability …

The aldosterone–renin ratio in screening for primary aldosteronism

M Stowasser, RD Gordon - The Endocrinologist, 2004 - journals.lww.com
Recognition that primary aldosteronism (PAL) is a common specifically treatable form of
hypertension and that most patients are normokalemic has led to a marked increase in …

The aldosterone to renin ratio in the diagnosis of primary aldosteronism: promises and challenges

PM O'Shea, TP Griffin, S Denieffe… - … journal of clinical …, 2019 - Wiley Online Library
The complexity of evaluating patients for secondary treatable causes of hypertension is
underappreciated. Primary aldosteronism (PA) is the most prevalent cause of secondary …

Aldosterone to renin ratio as screening tool in primary aldosteronism

K Schilbach, RK Junnila… - … Clinical Endocrinology & …, 2019 - thieme-connect.com
Primary aldosteronism (PA) is a severe and often underdiagnosed form of secondary
hypertension. Determining the aldosterone to renin ratio (ARR) in hypertensive patients has …

[HTML][HTML] Laboratory investigation of primary aldosteronism

M Stowasser, PJ Taylor, E Pimenta… - The Clinical …, 2010 - ncbi.nlm.nih.gov
Availability and wider application of the plasma aldosterone/renin ratio (ARR) as a
screening test for primary aldosteronism (PA) has led to the recognition that PA is the most …

A Renin-ssance in Primary Aldosteronism Testing: Obstacles and Opportunities for Screening, Diagnosis, and Management

JE Raizman, EP Diamandis, D Holmes… - Clinical …, 2015 - academic.oup.com
Primary aldosteronism (PA) 9 is a group of adrenal disorders characterized by autonomous
production of aldosterone independent of angiotensin II (AngII) stimulation. Idiopathic …

[PDF][PDF] Is primary aldosteronism rare or common among hypertensive patients?

T Nishikawa, J Saito, M Omura - Hypertension Research, 2007 - researchgate.net
The worldwide prevalence of primary aldosteronism (PA) among unselected patients with
hypertension is considered to be 10–15%(1, 2). However, there have always been wide …

Combination of LC–MS/MS aldosterone and automated direct renin in screening for primary aldosteronism

A Juutilainen, K Savolainen, J Romppanen… - Clinica Chimica …, 2014 - Elsevier
Background Aldosterone to renin ratio (ARR) is used in screening for primary aldosteronism
(PA). However, there are only few studies on the influence of assay methods on ARR and its …

Aldosterone, renin, and aldosterone-to-renin ratio variability in screening for primary aldosteronism

E Ng, SM Gwini, R Libianto, KW Choy… - The Journal of …, 2023 - academic.oup.com
Context The plasma aldosterone concentration (PAC), renin, and aldosterone-to-renin ratio
(ARR) are used to screen for primary aldosteronism (PA). Substantial intra-individual …