To understand the abnormalities that underpin functional gut disorders we must first gain
insight into the normal patterns of gut motility. While detailed information continually builds …

Background In recent years, high‐resolution manometry has been used in an attempt to gain
a greater insight into the physiology/pathophysiology of colonic contractile activity in healthy …

Alterations in colonic motility are implicated in the pathophysiology of bowel disorders, but
high-resolution manometry of human colonic motor function has revealed that our …

In recent years there have been significant technical and methodological advances in our
ability to record the movements of the gastrointestinal tract. This has led to significant …

Colonic motility disorders are common conditions. However, our understanding of normal,
and, consequently, pathological motor function of the colon remains limited, mainly due to …

The colon has an autonomic activity owing to the concerted actions of the interstitial cells of
Cajal, the enteric nervous system (especially myentric plexus and submucosal plexus), and …

As yet, there is limited information about the relationship of colonic motility to colonic flow or
transit. The overall flow in the colon is slow and highly variable. The measurement of total …

During the last decade, renewed interest in motility of the gastrointestinal tract has been
generated by a greater understanding of enteric neuroanatomy and neuropharmacology …

The ability to assess the complex motor functions of the gastrointestinal tract accurately has
been of tremendous value to understanding and treating digestive diseases. Unlike other …

Colonic motor patterns, which might become biomarkers of colonic dysmotility in
constipation, are still poorly defined in humans but have been clarified including the role of …