Immunization against the murine malaria parasite Plasmodium yoelii using a recombinant protein with adjuvants developed for clinical use
IT Ling, SA Ogun, P Momin, RL Richards, N Garcon… - Vaccine, 1997 - Elsevier
Mice vaccinated with a recombinant protein containing the two EGF-like modules of
Plasmodium yoelii merozoite surface protein-1 in liposomes or combined with the …
Plasmodium yoelii merozoite surface protein-1 in liposomes or combined with the …
Conversion of poorly immunogenic malaria repeat sequences into a highly immunogenic vaccine candidate
DR Milich, J Hughes, J Jones, M Sällberg, TR Phillips - Vaccine, 2001 - Elsevier
The recent success of a Plasmodium falciparum malaria vaccine consisting of
circumsporozoite protein (CSP) T and B cell epitopes has rekindled interest in the …
circumsporozoite protein (CSP) T and B cell epitopes has rekindled interest in the …
[HTML][HTML] Preclinical vaccine study of Plasmodium vivax circumsporozoite protein derived-synthetic polypeptides formulated in montanide ISA 720 and montanide ISA …
M Arévalo-Herrera, O Vera, A Castellanos… - The American journal …, 2011 - ncbi.nlm.nih.gov
Plasmodium vivax circumsporozoite (CS) protein is a leading malaria vaccine candidate
previously assessed in animals and humans. Here, combinations of three synthetic …
previously assessed in animals and humans. Here, combinations of three synthetic …
Identification of minimal human MHC-restricted CD8+ T-cell epitopes within the Plasmodium falciparum circumsporozoite protein (CSP)
M Sedegah, Y Kim, H Ganeshan, J Huang, M Belmonte… - Malaria journal, 2013 - Springer
Background Plasmodium falciparum circumsporozoite protein (CSP) is a leading malaria
vaccine candidate antigen, known to elicit protective antibody responses in humans (RTS, S …
vaccine candidate antigen, known to elicit protective antibody responses in humans (RTS, S …
Combination of protein and viral vaccines induces potent cellular and humoral immune responses and enhanced protection from murine malaria challenge
CL Hutchings, AJ Birkett, AC Moore… - Infection and …, 2007 - Am Soc Microbiol
The search for an efficacious vaccine against malaria is ongoing, and it is now widely
believed that to confer protection a vaccine must induce very strong cellular and humoral …
believed that to confer protection a vaccine must induce very strong cellular and humoral …
Improved T cell responses to Plasmodium falciparum circumsporozoite protein in mice and monkeys induced by a novel formulation of RTS, S vaccine antigen
P Mettens, PM Dubois, MA Demoitié, B Bayat… - Vaccine, 2008 - Elsevier
Protection against Plasmodium falciparum sporozoite infection can be achieved by
vaccination with the recombinant circumsporozoite protein-based vaccine RTS, S formulated …
vaccination with the recombinant circumsporozoite protein-based vaccine RTS, S formulated …
Soluble and glyco-lipid modified baculovirus Plasmodium falciparum C-terminal merozoite surface protein 1, two forms of a leading malaria vaccine candidate
Recombinant homologues of the Plasmodium merozoite surface protein 1 C-terminus are
leading blood stage malaria vaccine candidates. MSP1 is anchored to the merozoite plasma …
leading blood stage malaria vaccine candidates. MSP1 is anchored to the merozoite plasma …
Re-investigation of the circumsporozoite protein-based induction of sterile immunity against Plasmodium berghei infection
RC Reed, V Louis-Wileman, RL Wells, AFM Verheul… - Vaccine, 1996 - Elsevier
Although the circumsporozoite protein (CSP) of the malaria parasite is the most
immunologically characterized protein, the goal of using this protein in an effective vaccine …
immunologically characterized protein, the goal of using this protein in an effective vaccine …
Production and Preclinical Evaluation of Plasmodium falciparum MSP-119 and MSP-311 Chimeric Protein, PfMSP-Fu24
PK Gupta, P Mukherjee, S Dhawan… - Clinical and Vaccine …, 2014 - Am Soc Microbiol
ABSTRACT A Plasmodium falciparum chimeric protein, PfMSP-Fu24, was constructed by
genetically coupling immunodominant, conserved regions of two merozoite surface proteins …
genetically coupling immunodominant, conserved regions of two merozoite surface proteins …
Establishing RTS, S/AS01 as a benchmark for comparison to next-generation malaria vaccines in a mouse model
E Locke, Y Flores-Garcia, BT Mayer, RS MacGill… - npj Vaccines, 2024 - nature.com
New strategies are needed to reduce the incidence of malaria, and promising approaches
include vaccines targeting the circumsporozoite protein (CSP). To improve upon the malaria …
include vaccines targeting the circumsporozoite protein (CSP). To improve upon the malaria …