Background DNA methylation is a potential biomarker for early detection of breast cancer.
However, robust evidence of a prospective relationship between DNA methylation patterns …

Aberrant DNA methylation is a key feature of breast carcinoma. We aimed to test the
association between breast cancer risk and epigenome-wide methylation in DNA from …

Simple Summary As known breast cancer risk factors do not accurately predict the risk of
developing breast cancer, breast cancer screening is still based solely on age. At the …

Background Interest in the potential of DNA methylation in peripheral blood as a biomarker
of cancer risk is increasing. We aimed to assess whether epigenome-wide DNA methylation …

Until recently, an elevated disease risk has been ascribed to a genetic predisposition,
however, exciting progress over the past years has discovered alternate elements of …

Age is a key risk factor for breast cancer and epigenetic alterations may contribute to age-
related increases in breast cancer risk, though the relation of age-related methylation in …

Background Environmental and genetic factors play an important role in the etiology of
breast cancer. Several small blood-based DNA methylation studies have reported risk …

Epigenetic biomarkers, such as DNA methylation, can increase cancer risk through altering
gene expression. The Cancer Genome Atlas (TCGA) Network has demonstrated breast …

Background The underlying biological mechanisms through which epidemiologically
defined breast cancer risk factors contribute to disease risk remain poorly understood …

Background DNA methylation plays a critical role in breast cancer development. Previous
studies have identified DNA methylation marks in white blood cells as promising biomarkers …