The potential for various natural products to perturb the metabolism and disposition of
medications has been recognized for decades. There are numerous in vitro and in vivo …

Although there are inherent and recognized limitations of in vitro screening methodologies
to assess conventional drug-drug interactions (DDIs) per industry guidelines and those …

There is a continued predisposition of concurrent use of drugs and botanical products.
Consumers often self-administer botanical products without informing their health care …

The use of botanical dietary supplements has grown steadily over the last 20 years despite
incomplete information regarding active constituents, mechanisms of action, efficacy, and …

In Part 2 of this review, a critical examination of the pertinent scientific literature is
undertaken in order to assess the interaction risk that popular dietary supplements may pose …

Supported by a usage history that predates written records and the perception that “natural”
ensures safety, herbal products have increasingly been incorporated into Western health …

Herbal medicine (HM) is a type of medicine that uses active ingredients made from plants to
treat diseases and maintain health and wellbeing. Due to its increasing worldwide usage …

Although the potential of an interaction between concurrently administered botanical and
pharmaceutical products is not unexpected, this topic has received increased attention and …

The issue of herb-drug interactions has generated significant concern within the
pharmaceutical industry and among regulatory authorities in recent years. Therefore …

The interactions of natural products with drugs are discussed. Interactions between natural
products and drugs are based on the same pharmacokinetic and pharmacodynamic …