Herb–drug interactions: an overview of the clinical evidence

AA Izzo - Fundamental & clinical pharmacology, 2005 - Wiley Online Library
Herbal medicines are mixtures of more than one active ingredient. The multitude of
pharmacologically active compounds obviously increases the likelihood of interactions …

Drug-herb interaction among commonly used conventional medicines: a compendium for health care professionals

NC Brazier, MAH Levine - American Journal of Therapeutics, 2003 - journals.lww.com
The objective of the review was to consolidate the clinical and pharmacologic aspects of
drug–herb interactions to develop a compendium of information to provide prescribers with a …

Natural products: Experimental approaches to elucidate disposition mechanisms and predict pharmacokinetic drug interactions

MF Paine - Drug Metabolism and Disposition, 2020 - ASPET
Natural products have been used by humans since antiquity for both egregious and
beneficial purposes. Regarding the latter, these products have long been valued as a rich …

Herb-drug interactions: a review.

AS Thomas, P Varughese, A Shirwaikar, A Shirwaikar - 2012 - cabidigitallibrary.org
Herbal drugs are exempt from Food and Drug Administration regulations regarding efficacy
and safety. Their potential of interaction with conventional prescription drugs is a matter of …

Recommended approaches for pharmacokinetic natural product-drug interaction research: a NaPDI center commentary

MF Paine, DD Shen, JS McCune - Drug Metabolism and Disposition, 2018 - ASPET
Sales of botanical dietary supplements and other purported medicinal natural products
(NPs) have escalated over the past∼ 25 years, increasing the potential for NPs to …

Drug-herb interactions: eliminating toxicity with hard drug design

XX Yang, ZP Hu, W Duan, YZ Zhu… - Current pharmaceutical …, 2006 - ingentaconnect.com
By searching the literatures, it was found that a total of 32 drugs interacting with herbal
medicines in humans. These drugs mainly include anticoagulants (warfarin, aspirin and …

Clinical evidence of herbal drugs as perpetrators of pharmacokinetic drug interactions

R Hermann, O von Richter - Planta medica, 2012 - thieme-connect.com
The use of herbal/botanical products, also referred to as complementary and alternative
medicines (CAM), worldwide enjoys increasing popularity. It appears in particular highly …

[引用][C] Understanding drug–herb interactions

NC Brazier, MAH Levine - Pharmacoepidemiology and drug …, 2003 - Wiley Online Library
BACKGROUND In the last decade, the use of herbal medicines has increased by
unprecedented proportions. Evidence from the USA indicates that herbal medication use …

Quantitative prediction and clinical evaluation of an unexplored herb–drug interaction mechanism in healthy volunteers

BT Gufford, JT Barr, V González‐Pérez… - CPT …, 2015 - Wiley Online Library
Quantitative prediction of herb–drug interaction risk remains challenging. A quantitative
framework to assess a potential interaction was used to evaluate a mechanism not …

Current regulatory toxicology perspectives on the development of herbal medicines to prescription drug products in the United States

KM Wu, H Ghantous, DB Birnkrant - Food and chemical toxicology, 2008 - Elsevier
Toxicological studies constitute an essential part of the effort in developing an herbal
medicine into a drug product. The US food and drug administration (FDA) published a …