The clinical importance of herb-drug interactions and toxicological risks of plants and herbal products

C Kahraman, ZC Arituluk, IIT Cankaya - Medical Toxicology, 2020 - books.google.com
Approximately 70% of the world's population has been using medicinal herbs as a
complementary or alternative medicine that has grown tremendously in both developed and …

Herb–drug pharmacokinetic interactions reviewed

C Tarirai, AM Viljoen, JH Hamman - Expert opinion on drug …, 2010 - Taylor & Francis
Importance of the field: The global increase in the popularity of alternative medicines has
raised renewed concerns regarding herb–drug interactions. These interactions are …

In vivo assessment of herb–drug interactions: Possible utility of a pharmacogenetic approach?

B Tomlinson, M Hu, VWY Lee - Molecular nutrition & food …, 2008 - Wiley Online Library
Herbal medicines are frequently used in combination with conventional drugs and
interactions are likely to be more common than those which manifest clinically …

Clinical risk management of interactions between natural products and drugs

PAGM De Smet, A Floor-Schreudering… - Current drug …, 2008 - ingentaconnect.com
Clinical risk management offers a systematic approach to minimize healthcare-related risks
by paying attention to:(1) risk identification and assessment;(2) development and execution …

Follow that botanical: Challenges and recommendations for assessing absorption, distribution, metabolism and excretion of botanical dietary supplements

S Waidyanatha, K Ryan, AL Roe, W Jia… - Food and chemical …, 2018 - Elsevier
Botanical dietary supplements are complex mixtures containing one or more botanical
ingredient (s), each containing numerous constituents potentially responsible for its …

Herb–drug interactions: A mechanistic approach

AK Sharma, VK Kapoor, G Kaur - Drug and Chemical Toxicology, 2022 - Taylor & Francis
In India, traditional herbal medicines have been an essential part of therapy for the last
centuries. However, a large portion of the general populace is using these therapies in …

Drug‐Drug, Drug—Dietary Supplement, and Drug—Citrus Fruit and Other Food Interactions: What Have We Learned?

SM Huang, LJ Lesko - The Journal of Clinical Pharmacology, 2004 - Wiley Online Library
Serious drug‐drug interactions have contributed to recent US market withdrawals and also
recent nonapprovals of a few new molecular entities. Many of these interactions involved the …

Herb–drug, food–drug, nutrient–drug, and drug–drug interactions: mechanisms involved and their medical implications

JM Sørensen - The Journal of Alternative & Complementary …, 2002 - liebertpub.com
Adverse drug reactions (ADRs) and iatrogenic diseases have been identified as significant
factors responsible for patient morbidity and mortality. Significant studies on drug …

Herbs–are they safe enough? An overview

D Singh, R Gupta, SA Saraf - Critical reviews in food science and …, 2012 - Taylor & Francis
Drugs based on herbs have become a common form of therapy as well as for prophylaxis
because they are often perceived as being natural and therefore harmless. Today they are …

Regulatory science: a special update from the United States Food and Drug Administration: Preclinical issues and status of investigation of botanical drug products in …

KM Wu, JG DeGeorge, A Atrakchi, E Barry, A Bigger… - Toxicology letters, 2000 - Elsevier
A recent survey was conducted across the therapeutic divisions within the CDER, US FDA
regarding the number of submissions related to botanical drug products over the past ten …