Inhibition of human allergic T-cell responses by IL-10–treated dendritic cells: Differences from hydrocortisone-treated dendritic cells

I Bellinghausen, U Brand, K Steinbrink, AH Enk… - Journal of allergy and …, 2001 - Elsevier
Background: Dendritic cells (DCs) are able to induce human allergic TH1 responses as well
as TH2 responses. Objective: In this study, we examined the effect of antiinflammatory …

Comparison of allergen-stimulated dendritic cells from atopic and nonatopic donors dissecting their effect on autologous naive and memory T helper cells of such …

I Bellinghausen, U Brand, J Knop, J Saloga - Journal of allergy and clinical …, 2000 - Elsevier
Background: Because of their production of IL-12, mature dendritic cells (DC) are potent
inducers of TH1 responses. However, recent reports have demonstrated that DCs can also …

Helper T-cell responses elicited by Der p 1–pulsed dendritic cells and recombinant IL-12 in atopic and healthy subjects

D De Wit, Z Amraoui, B Vincart, O Michel… - Journal of allergy and …, 2000 - Elsevier
Background: Environmental allergens, such as Dermatophagoides pteronyssinus group 1
antigen (Der p 1), induce TH2-type responses in atopic patients, whereas healthy …

Increase of dendritic cells of type 2 (DC2) by altered response to IL-4 in atopic patients

Y Uchida, K Kurasawa, H Nakajima… - Journal of allergy and …, 2001 - Elsevier
Background: Recent studies have shown that there are 2 dendritic cell subpopulations, DC1
and DC2, which induce TH1 and TH2 cell differentiation in vitro, respectively. Objective: The …

Inhibition of human allergic T‐helper type 2 immune responses by induced regulatory T cells requires the combination of interleukin‐10‐treated dendritic cells and …

I Bellinghausen, B König, I Böttcher… - Clinical & …, 2006 - Wiley Online Library
Background In grass pollen‐allergic individuals, T cell anergy can be induced by IL‐10‐
treated dendritic cells (IL‐10‐DC) resulting in the suppression of T helper type 1 (Th1) as …

Dendritic cells contribute to the development of atopy by an insufficiency in IL-12 production

N Reider, D Reidera, S Ebner, S Holzmann… - Journal of allergy and …, 2002 - Elsevier
Background: IL-12 is a crucial factor in the development and course of allergic diseases. By
virtue of their IL-12 production, dendritic cells (DCs) are potent inducers of TH1 responses …

Induction of type 2 T helper cell allergen tolerance by IL-10–differentiated regulatory dendritic cells

X Li, A Yang, H Huang, X Zhang, J Town… - American journal of …, 2010 - atsjournals.org
In mouse models of asthma, therapeutic use of allergen-presenting IL-10–differentiated
dendritic cells (DCs) can abrogate airway hyperresponsiveness, and reduce other asthma …

Fluticasone propionate increases CD4+ CD25+ T regulatory cell suppression of allergen-stimulated CD4+ CD25− T cells by an IL-10–dependent mechanism

XD Nguyen, DS Robinson - Journal of allergy and clinical immunology, 2004 - Elsevier
BACKGROUND: Corticosteroids are the most effective anti-inflammatory therapy for allergic
diseases, and these drugs inhibit TH2 T-cell activation. We previously reported that CD4+ …

Induction of anergic allergen-specific suppressor T cells using tolerogenic dendritic cells derived from children with allergies to house dust mites

V Pacciani, S Gregori, L Chini, S Corrente… - Journal of allergy and …, 2010 - Elsevier
BACKGROUND: Dendritic cells (DCs) regulate the immune response to allergens in the
lung; they induce either effector or regulatory T cells, which promote or suppress …

Role of regulatory dendritic cells in allergy and asthma

O Akbari, DT Umetsu - Current Opinion in Allergy and Clinical …, 2004 - journals.lww.com
Role of regulatory dendritic cells in allergy and asthma : Current Opinion in Allergy and Clinical
Immunology Role of regulatory dendritic cells in allergy and asthma : Current Opinion in Allergy …