A vaccine against malaria is urgently needed for control and eventual eradication. Different
approaches are pursued to induce either sterile immunity directed against pre-erythrocytic …

An effective vaccine would be a valuable tool for malaria control and elimination; however,
the leading malaria vaccine in development, RTS, S/AS01, provided only partial protection …

Transgenic (Tg) mice carrying a T‐cell receptor (TCR) specific for a CD8+ T‐cell epitope
expressed in pre‐erythrocytic stages of Plasmodium yoelii has proven to be a valuable tool …

The induction of cellular immunity, in conjunction with antibodies, may be essential for
vaccines to protect against blood-stage infection with the human malaria parasite …

The development of a vaccine is essential for the elimination of malaria. However, despite
many years of effort, a successful vaccine has not been achieved. Most subunit vaccine …

Despite nearly 100 years of research and control efforts, malaria remains one of the most
important infectious diseases. An efficient vaccine would be a powerful to tool to reduce …

Hepatocyte infection by malaria sporozoites is a bottleneck in the life-cycle of Plasmodium
spp. including P. falciparum, which causes the most lethal form of malaria. Therefore …

Plasmodium falciparum malaria remains one of the most serious health problems globally
and a protective malaria vaccine is desperately needed. Vaccination with attenuated …

Despite major efforts over the past 50 years to develop a malaria vaccine, no product has
been licensed yet. Irradiated sporozoites are the benchmark for an experimental live …

The Plasmodium‐infected hepatocyte has been considered necessary to prime the immune
responses leading to sterile protection after vaccination with attenuated sporozoites …