Prospects for Malaria Vaccines: Pre‐Erythrocytic Stages, Blood Stages, and Transmission‐Blocking Stages

J Zheng, H Pan, Y Gu, X Zuo, N Ran… - BioMed research …, 2019 - Wiley Online Library
Malaria is a disease of public health importance in many parts of the world. Currently, there
is no effective way to eradicate malaria, so developing safe, efficient, and cost‐effective …

[PDF][PDF] Progress with new malaria vaccines

D Webster, AVS Hill - Bulletin of the World Health …, 2003 - SciELO Public Health
Malaria is a parasitic disease of major global health significance that causes an estimated
2.7 million deaths each year. In this review we describe the burden of malaria and discuss …

Plasmodium falciparum malaria vaccines in development

J Vekemans, WR Ballou - Expert review of vaccines, 2008 - Taylor & Francis
The development and implementation of a malaria vaccine would constitute a major
breakthrough for global health. Recently, numerous new candidates have entered clinical …

Towards a blood-stage vaccine for malaria: are we following all the leads?

MF Good - Nature Reviews Immunology, 2001 - nature.com
Although the malaria parasite was discovered more than 120 years ago, it is only during the
past 20 years, following the cloning of malaria genes, that we have been able to think …

Vaccines against malaria–an update

K Matuschewski, AK Mueller - The FEBS journal, 2007 - Wiley Online Library
Malaria vaccine discovery and development follow two principal strategies. Most subunit
vaccines are designed to mimic naturally acquired immunity that develops over years upon …

Vaccines against malaria

A Ouattara, MB Laurens - Clinical Infectious Diseases, 2015 - academic.oup.com
Despite global efforts to control malaria, the illness remains a significant public health threat.
Currently, there is no licensed vaccine against malaria, but an efficacious vaccine would …

Steady progress toward a malaria vaccine

KE Lyke - Current Opinion in Infectious Diseases, 2017 - journals.lww.com
Vaccines are the most cost-effective tools to control infectious diseases, yet the complexity of
malaria has frustrated all attempts to develop an effective product. This review concentrates …

[HTML][HTML] Malaria vaccines and the new malaria agenda

BM Greenwood, GAT Targett - Clinical Microbiology and Infection, 2011 - Elsevier
The development of an effective malaria vaccine has taken many decades, but there is now
a good chance that the first malaria vaccine will be licensed within the next few years …

Blood-stage malaria vaccines—recent progress and future challenges

AL Goodman, SJ Draper - Annals of Tropical Medicine & …, 2010 - Taylor & Francis
Plasmodium falciparum malaria is a major global health problem, responsible for up to 1
million deaths each year. Major efforts have been made to develop an effective vaccine …

Pre-erythrocytic malaria vaccines: towards greater efficacy

AVS Hill - Nature Reviews Immunology, 2006 - nature.com
The complex life cycle of the malaria parasite Plasmodium falciparum provides many
options for vaccine design. Several new types of vaccine are now being evaluated in clinical …