Immunological memory is one of the features that define the adaptive immune response: by
generating specific memory cells after infection or vaccination, the host provides itself with a …

The development of immune memory mediated by T lymphocytes is central to durable, long‐
lasting protective immunity. A key issue in the field is how to direct the generation and …

The ability to develop and sustain populations of memory T cells after infection or
immunization is a hallmark of the adaptive immune response and a basis for protective …

While many aspects of memory T‐cell immunobiology have been characterized, we suggest
that we know only a fraction of the effector functions that CD4 T cells can bring to bear during …

Following infection, T cells differentiate into a heterogeneous population of effector T cells
that can mediate pathogen clearance. A subset of these effector T cells possesses the ability …

Immunologic memory is the adaptive immune system's powerful ability to remember a
previous antigen encounter and react with accelerated vigor upon antigen re-exposure. It …

Immunological memory is one of the defining features of the adaptive immune system. As
key orchestrators and mediators of immunity, CD4 T cells are central to the vast majority of …

The immune system has evolved by continuously increasing its complexity to provide the
host with an advantage over infectious agents. The development of immunological memory …

Immunological memory provides the basis for successful vaccines. It is important to
understand the properties of memory cells. There is much known about the phenotype and …

An important goal of vaccination strategies is to elicit long term, effective immunity. Therefore
it is imperative to define the parameters that regulate the development and preservation of …